Cover photograph (Copyright © 2000, American Society for Microbiology. All rights reserved.): Expression of the enhanced green fluorescent protein (EGFP) gene in ependymal cells of the rat brain. An F-defective Sendai virus vector that is capable of self-replication but incapable of transmissible virion production was injected into an intraventricular region of the rat brain at a dose of 2 × 10⁷ cell infectious units. Shown is a fluorescence photomicrograph of the rat brain taken 4 days after vector injection. Efficient introduction and expression of EGFP are observed in ependymal cells of the lateral ventricle. (See related article in July 2000, issue 14: vol. 74, p. 6564.)