Isolation and Characterization of H4N6 Avian Influenza Viruses from Pigs with Pneumonia in Canada

  1. Christopher W. Olsen1,*
  1. Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin—Madison, Madison, Wisconsin 537061;
  2. Veterinary Laboratory Agency—Weybridge, New Haw, Addlestone, Surrey KT15 3NB, United Kingdom2; and
  3. Animal Health Laboratory, University of Guelph, Guelph, Ontario N1H 6R8, Canada3

ABSTRACT

In October 1999, H4N6 influenza A viruses were isolated from pigs with pneumonia on a commercial swine farm in Canada. Phylogenetic analyses of the sequences of all eight viral RNA segments demonstrated that these are wholly avian influenza viruses of the North American lineage. To our knowledge, this is the first report of interspecies transmission of an avian H4 influenza virus to domestic pigs under natural conditions.

FOOTNOTES

    • Received 16 May 2000.
    • Accepted 14 July 2000.
  • * Corresponding author. Mailing address: Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin—Madison, 2015 Linden Dr. West, Madison, WI 53706. Phone: (608) 265-8681. Fax: (608) 263-0438. E-mail:olsenc{at}svm.vetmed.wisc.edu.

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