JVI Figure table search 04
Home Help [Feedback] [For Subscribers] [Archive] [Search] --
JVI Accepts, published online ahead of print on 19 March 2008
This Article
Right arrow Full Text (PDF)
Right arrow Other Versions of this Article:
JVI.02722-07v1
82/10/5084    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Google Scholar
Right arrow Articles by Mihindukulasuriya, K. A.
Right arrow Articles by Wang, D.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mihindukulasuriya, K. A.
Right arrow Articles by Wang, D.

 Previous Article  |  Next Article 

J. Virol. doi:10.1128/JVI.02722-07
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Identification of a Novel Coronavirus from a Beluga Whale Using a Pan-viral Microarray

Kathie A. Mihindukulasuriya, Guang Wu, Judy St. Leger, Robert W. Nordhausen, and David Wang*

Departments of Molecular Microbiology and Pathology & Immunology, Washington University School of Medicine, St. Louis, MO USA; SeaWorld, San Diego, 500 SeaWorld Dr. San Diego, CA 92109 USA; California Animal Health and Food Safety Laboratory, University of California at Davis, West Health Science Drive, Davis, CA 95616 USA

* To whom correspondence should be addressed. Email: davewang{at}borcim.wustl.edu.


  Abstract

The emergence of viruses such as SARS and Nipah has underscored the role of animal reservoirs in human disease and the need for reservoir surveillance. Here, we used a pan-viral DNA microarray to investigate the death of a captive beluga whale in an aquatic park. A highly divergent coronavirus, tentatively named coronavirus SW1, was identified in liver tissue from the deceased whale. Subsequently, the entire genome of SW1 was sequenced yielding a genome of 31,686 nucleotides. Phylogenetic analysis revealed SW1 to be a novel virus distantly related to, but most similar to group III coronaviruses.




This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] --
J. Bacteriol. Mol. Cell. Biol. Microbiol. Mol. Biol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2008 by the American Society for Microbiology. All rights reserved.