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Journal of Virology, August 2006, p. 7760-7764, Vol. 80, No. 15
0022-538X/06/$08.00+0     doi:10.1128/JVI.00445-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

H7N3 Avian Influenza Virus Found in a South American Wild Duck Is Related to the Chilean 2002 Poultry Outbreak, Contains Genes from Equine and North American Wild Bird Lineages, and Is Adapted to Domestic Turkeys

Erica Spackman,1* Kevin G. McCracken,2,3 Kevin Winker,2 and David E. Swayne1

Southeast Poultry Research Laboratory, USDA-ARS, 934 College Station Road, Athens, Georgia 30605,1 Institute of Arctic Biology and Department of Biology and Wildlife,2 University of Alaska Museum, 907 Yukon Drive, Fairbanks, Alaska 997752

Received 2 March 2006/ Accepted 9 May 2006

An H7N3 avian influenza virus (AIV) was isolated from a Cinnamon Teal (Anas cyanoptera) (A/CinnamonTeal/Bolivia/4537/01) during a survey of wild waterfowl in Bolivia in 2001. The NA and M genes had the greatest identity with North American wild bird isolates, the NS was most closely related to an equine virus, and the remaining genes were most closely related to isolates from an outbreak of H7N3 in commercial poultry in Chile in 2002. The HA protein cleavage site and the results of pathogenesis studies in chickens were consistent with a low-pathogenicity virus, and the infective dose was 105 times higher for chickens than turkeys.


* Corresponding author. Mailing address: Southeast Poultry Research Laboratory, USDA, ARS, 934 College Station Rd., Athens, GA 30605. Phone: (706) 546-3617. Fax: (706) 546-3161. E-mail: espackman{at}seprl.usda.gov.


Journal of Virology, August 2006, p. 7760-7764, Vol. 80, No. 15
0022-538X/06/$08.00+0     doi:10.1128/JVI.00445-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:

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  • Lang, A. S., Kelly, A., Runstadler, J. A. (2008). Prevalence and diversity of avian influenza viruses in environmental reservoirs. J. Gen. Virol. 89: 509-519 [Abstract] [Full Text]