This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Adamson, A. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Adamson, A. L.

 Previous Article  |  Next Article 

Journal of Virology, June 2005, p. 7899-7904, Vol. 79, No. 12
0022-538X/05/$08.00+0     doi:10.1128/JVI.79.12.7899-7904.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Epstein-Barr Virus BZLF1 Protein Binds to Mitotic Chromosomes

Amy L. Adamson*

Department of Biology, University of North Carolina at Greensboro, Greensboro, North Carolina 27402

Received 3 November 2004/ Accepted 14 February 2005

Epstein-Barr virus (EBV) is a human herpesvirus that causes infectious mononucleosis and is associated with several types of cancers, including nasopharyngeal carcinoma and Burkitt's lymphoma. An EBV protein that plays an integral role during lytic replication is the immediate-early protein BZLF1. Our laboratory has found that BZLF1 (Z) localizes to host chromosomes during mitosis. Two Z-interacting proteins are also found localized to mitotic chromosomes in the presence of Z. The association between Z and mitotic chromosomes may lead to the sequestering of Z-interacting proteins within the cell and potentially cause an alteration of chromosome compaction or chromatin structure.

* Mailing address: Department of Biology, University of North Carolina at Greensboro, Greensboro, NC 27402. Phone: (336) 256-0312. Fax: (336) 334-5839. E-mail: aladamso{at}uncg.edu.

Journal of Virology, June 2005, p. 7899-7904, Vol. 79, No. 12
0022-538X/05/$08.00+0     doi:10.1128/JVI.79.12.7899-7904.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Tedeschi, R., Bloigu, A., Ogmundsdottir, H. M., Marus, A., Dillner, J., dePaoli, P., Gudnadottir, M., Koskela, P., Pukkala, E., Lehtinen, T., Lehtinen, M. (2007). Activation of Maternal Epstein-Barr Virus Infection and Risk of Acute Leukemia in the Offspring. Am J Epidemiol 165: 134-137 [Abstract] [Full Text]  
  • Adamson, A. L., Wright, N., LaJeunesse, D. R. (2005). Modeling Early Epstein-Barr Virus Infection in Drosophila melanogaster: The BZLF1 Protein. Genetics 171: 1125-1135 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»