This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Albrecht, J.-C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Albrecht, J.-C.

 Previous Article  |  Next Article 

Journal of Virology, January 2000, p. 1033-1037, Vol. 74, No. 2
0022-538X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Primary Structure of the Herpesvirus Ateles Genomedagger

Jens-Christian Albrecht*

Institut für Klinische und Molekulare Virologie, Universität Erlangen-Nürnberg, 91054 Erlangen, Germany

Received 21 June 1999/Accepted 19 October 1999

Herpesvirus ateles is an agent indigenous to spider monkeys (Ateles spp.) and causes fulminant lymphomas in various New World primates. Structural and genetic relatedness led to the classification of this virus as a member of the genus Rhadinovirus. It is most closely related to Herpesvirus saimiri. The 108,409-bp light DNA segment of the herpesvirus ateles strain 73 genome has two genes for U-RNA-like transcripts and 73 open reading frames, of which at least 6 show significant homologies to cellular genes (encoding complement control proteins, apoptosis-regulatory proteins, D-type cyclins, interleukin-8 receptors, and enzymes involved in nucleotide metabolism). The left terminal region of the light DNA segment bears the putative rhadinovirus oncogene tio.

* Mailing address: Institut für Klinische und Molekulare Virologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schlossgarten 4, D-91054 Erlangen, Germany. Phone: 49-9131-8526483. Fax: 49-9131-8526493. E-mail: jsalbrec{at}viro.med.uni-erlangen.de.

dagger To the memory of my father.

Journal of Virology, January 2000, p. 1033-1037, Vol. 74, No. 2
0022-538X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Gao, J., Coulson, J. M., Whitehouse, A., Blake, N. (2009). Reduction in RNA Levels Rather than Retardation of Translation Is Responsible for the Inhibition of Major Histocompatibility Complex Class I Antigen Presentation by the Glutamic Acid-Rich Repeat of Herpesvirus Saimiri Open Reading Frame 73. J. Virol. 83: 273-282 [Abstract] [Full Text]  
  • Brinkmann, M. M., Schulz, T. F. (2006). Regulation of intracellular signalling by the terminal membrane proteins of members of the Gammaherpesvirinae.. J. Gen. Virol. 87: 1047-1074 [Abstract] [Full Text]  
  • CONRAD, N.K., FOK, V., CAZALLA, D., BORAH, S., STEITZ, J.A. (2006). The Challenge of Viral snRNPs. Cold Spring Harb Symp Quant Biol 71: 377-384 [Abstract]  
  • Albrecht, J.-C., Muller-Fleckenstein, I., Schmidt, M., Fleckenstein, B., Biesinger, B. (2005). Tyrosine Phosphorylation of the Tio Oncoprotein Is Essential for Transformation of Primary Human T Cells. J. Virol. 79: 10507-10513 [Abstract] [Full Text]  
  • McGeoch, D. J., Gatherer, D., Dolan, A. (2005). On phylogenetic relationships among major lineages of the Gammaherpesvirinae. J. Gen. Virol. 86: 307-316 [Abstract] [Full Text]  
  • Golembe, T. J., Yong, J., Battle, D. J., Feng, W., Wan, L., Dreyfuss, G. (2005). Lymphotropic Herpesvirus saimiri Uses the SMN Complex To Assemble Sm Cores on Its Small RNAs. Mol. Cell. Biol. 25: 602-611 [Abstract] [Full Text]  
  • Albrecht, J.-C., Biesinger, B., Muller-Fleckenstein, I., Lengenfelder, D., Schmidt, M., Fleckenstein, B., Ensser, A. (2004). Herpesvirus Ateles Tio Can Replace Herpesvirus Saimiri StpC and Tip Oncoproteins in Growth Transformation of Monkey and Human T Cells. J. Virol. 78: 9814-9819 [Abstract] [Full Text]  
  • Cook, H. L., Mischo, H. E., Steitz, J. A. (2004). The Herpesvirus saimiri Small Nuclear RNAs Recruit AU-Rich Element-Binding Proteins but Do Not Alter Host AU-Rich Element-Containing mRNA Levels in Virally Transformed T Cells. Mol. Cell. Biol. 24: 4522-4533 [Abstract] [Full Text]  
  • de Thoisy, B., Pouliquen, J.-F., Lacoste, V., Gessain, A., Kazanji, M. (2003). Novel Gamma-1 Herpesviruses Identified in Free-Ranging New World Monkeys (Golden-Handed Tamarin [Saguinus midas], Squirrel Monkey [Saimiri sciureus], and White-Faced Saki [Pithecia pithecia]) in French Guiana. J. Virol. 77: 9099-9105 [Abstract] [Full Text]  
  • Rose, T. M., Ryan, J. T., Schultz, E. R., Raden, B. W., Tsai, C.-C. (2003). Analysis of 4.3 Kilobases of Divergent Locus B of Macaque Retroperitoneal Fibromatosis-Associated Herpesvirus Reveals a Close Similarity in Gene Sequence and Genome Organization to Kaposi's Sarcoma-Associated Herpesvirus. J. Virol. 77: 5084-5097 [Abstract] [Full Text]  
  • Lacoste, V., Mauclere, P., Dubreuil, G., Lewis, J., Georges-Courbot, M.-C., Gessain, A. (2001). A Novel gamma 2-Herpesvirus of the Rhadinovirus 2 Lineage in Chimpanzees. Genome Res 11: 1511-1519 [Abstract] [Full Text]  
  • Nicholas, J (2000). Evolutionary aspects of oncogenic herpesviruses. Mol. Pathol. 53: 222-237 [Abstract] [Full Text]  
  • Schultz, E. R., Rankin, G. W. Jr., Blanc, M.-P., Raden, B. W., Tsai, C.-C., Rose, T. M. (2000). Characterization of Two Divergent Lineages of Macaque Rhadinoviruses Related to Kaposi's Sarcoma-Associated Herpesvirus. J. Virol. 74: 4919-4928 [Abstract] [Full Text]  
  • Greensill, J., Sheldon, J. A., Renwick, N. M., Beer, B. E., Norley, S., Goudsmit, J., Schulz, T. F. (2000). Two Distinct Gamma-2 Herpesviruses in African Green Monkeys: a Second Gamma-2 Herpesvirus Lineage among Old World Primates?. J. Virol. 74: 1572-1577 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»