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Journal of Virology, August 1999, p. 7077-7079, Vol. 73, No. 8
0022-538X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Expression of the Coxsackievirus and Adenovirus Receptor in Cultured Human Umbilical Vein Endothelial Cells: Regulation in Response to Cell Density

Steven D. Carson,* Justin T. Hobbs, Steven M. Tracy, and Nora M. Chapman

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198-6495

Received 18 March 1999/Accepted 11 May 1999

Primary cultures of human umbilical vein endothelial cells (HUVEC) express the human coxsackievirus and adenovirus receptor (HCAR). Whereas HCAR expression in HeLa cells was constant with respect to cell density, HCAR expression in HUVEC increased with culture confluence. HCAR expression in HUVEC was not quantitatively altered by infection with coxsackievirus B.

* Corresponding author. Mailing address: Department of Pathology and Microbiology, 986495 Nebraska Medical Center, Omaha, NE 68198-6495. Phone: (402) 559-4710. Fax: (402) 559-4077. E-mail: 73632.3623{at}compuserve.com.

Journal of Virology, August 1999, p. 7077-7079, Vol. 73, No. 8
0022-538X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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