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Journal of Virology, October 1999, p. 8890-8897, Vol. 73, No. 10
0022-538X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Assessment of Bovine Leukemia Virus Transcripts In Vivo

Joel Rovnak* and James W. Casey

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853

Received 16 February 1999/Accepted 9 July 1999

Reverse transcriptase PCR (RT-PCR) consistently detected bovine leukemia virus transcripts in fresh cells, and competitive RT-PCR enumerated these transcripts. The detection of transcripts in limited numbers of tumor cells indicated that expression occurs in a minority of cells. The data suggest that individual cells contain hundreds of copies of the tax/rex transcript in vivo.

* Corresponding author. Present address: Department of Molecular Biosciences, 7047 Haworth Hall, University of Kansas, Lawrence, KS 66045-2106. Phone: (785) 864-4022. Fax: (785) 864-5294. E-mail: jr38{at}cornell.edu.

Journal of Virology, October 1999, p. 8890-8897, Vol. 73, No. 10
0022-538X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

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