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J Virol. 1987 February; 61(2): 604-606

A mutant of herpes simplex virus type 1 exhibits increased stability of immediate-early (alpha) mRNAs.

A A Oroskar and G S Read

ABSTRACT

vhs1 is a herpes simplex virus type 1 mutant defective in the shutoff of both host and alpha polypeptide synthesis. In cycloheximide reversal experiments, alpha mRNAs were significantly more stable in vhs1-infected cells than in cells infected with wild-type virus, whether assayed by in vitro translation or Northern blotting.

J Virol. 1987 February; 61(2): 604-606




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