Files in this Data Supplement:

• Supplemental file 1 - Fig. S1 (Rescue of IFN-β induction by transfected dsRNA in MAVS−/− MEFs.)
  Fig. S2 (Activity of RIG-I mutants lacking their C-terminal repressor domains.)
  Fig. S3 (Activity of fused MAVS homodimeric constructs.)
  Fig. S4 (Yeast two-hybrid interaction between MAVS and TRAF3.)
  Fig. S5 (Importance of the CARD domain for MAVS function.)
  Zipped MS PPT file, 2.5MB.