Files in this Data Supplement:

• Supplemental file 1 - Legends to Fig. S1 to S6
  MS Word document, 35K.
• Supplemental file 2 - Fig. S1 (Amino acid sequences of gp160 and mutant mosaics and best natural sequences.)
  Zipped PDF file, 36K.
• Supplemental file 3 - Fig. S2 (gp160ΔCFI mos 2 and mos 3 mosaics elicited more breadth of CD8 T-cell responses than gp160ΔCFI single mosaic, the two gp160ΔCFI natural strains sets, and gp145ΔCFI clades A, B, and C.)
  Zipped PDF file, 323K.
• Supplemental file 4 - Fig. S3 (gp160ΔVΔCFI mos 3 mosaics elicited similar breadth of CD8⁺ T-cell responses as gp160ΔCFI mos 3 mosaics but less than gp160 mos 3 mosaics.)
  Zipped PDF file, 300K.
• Supplemental file 5 - Fig. S4 (gp145ΔCFI mosaics showed minimal CD8⁺ T-cell responses to PTE peptide pool.)
  Zipped PDF file, 300K.
• Supplemental file 6 - Fig. S5 (gp160ΔV mosaics elicit fewer CD8⁺ T-cell responses than gp160 mosaics.)
  Zipped PDF file, 252K.
• Supplemental file 7 - Fig. S6 (Matched 9-mers by pool for vaccine candidates.)
  Zipped PDF file, 160K.
• Supplemental file 8 - Table S1 (The number of plates for each combination of vaccine and modification.)
  Table S2 (Experimental design of different antigens analyzed in this study.)
  Table S3 (Match counts between 9-mers found in vaccines (gp160 unmodified) and PTE peptide pools.)
  Zipped MS Word document, 10K.