Files in this Data Supplement:

• Supplemental file 1 - Supplemental material
  Fig. S1 (Swarm analysis of quasispecies from one individual infected with HIV, for the identification of mutations that confer sensitivity and resistance to broadly neutralizing antibodies.)
  Fig. S2 (Infectivity screen to identify envelope clones for use in neutralization assay.)
  Fig. S3 (Neutralization of mutants from clone 22 of subject 108060.)
  Fig. S4 (Conformational transitions involved formation of the fusion-active 6-helix bundle in gp41.)
  PDF file, 292K.