Induction of Broad CD4+ and CD8+ T-Cell Responses and Cross- Neutralizing Antibodies against Hepatitis C Virus by Vaccination with Th1-Adjuvanted Polypeptides Followed by Defective Alphaviral Particles Expressing Envelope Glycoproteins gpE1 and gpE2 and Nonstructural Proteins 3, 4, and 5
J. Virol. Lin et al.
82: 7492
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
-
Fig. S1 (Detection of HCV protein expression from VEE/SIN replicon particles by Western blotting.)
Fig. S2 (Detection of CD4+ and CD8+ T-cell responses by ICS/FACS.)
Fig. S3 (VEE/SIN-E1E2 immunization and prime/boost regime with E1E2/MF59 and VEE/SIN-E1E2 could stimulate good CD8+ T-cell responses.)
MS PPT file, 342K.
