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In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses
J. Virol. Grimm et al. 82: 5887

Supplemental material

Files in this Data Supplement:

  • Supplemental file 1 - Fig. S1 (Nucleotide sequences of 12 randomly chosen clones from the unselected library, 5′ ends.)
    Fig. S2 (Nucleotide sequences of 12 randomly chosen clones from the unselected library, 3′ ends.)
    Fig. S3 (Selection of shuffled AAV capsids with human immunoglobulin IVIG.)
    Fig. S4 (Protein sequence alignment of AAV-DJ and the 8 parental viruses.)
    Fig. S5 (Analyses of liver vector DNA.)
    Fig. S6 (Amino acid frequencies in AAV peptide display libraries before and after selection.)
    PDF document, 487K.




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