This work was supported by NIH AREA grant AI41165 to J.H.N.
We thank Jim Rusche and Carolyn Muermann (Repligen Corp.) for gifts of
V3-directed MAbs 50.1, 58.2, and 59.1. Additional reagents were kindly
provided by Steve Chamow (Genentech, Inc.), Dan Littman (HHMI, NYU
Medical Center), Ian Clark-Lewis (University of British Columbia),
Susan Zolla-Pazner (NYU Medical Center), and Fred Prince (NY Blood
Center). The following MAbs were obtained through the AIDS Research and
Reference Reagent Program, NIH, NIAID: 2D7 from LeukoSite, Inc.,
and IgG1 b12 from Dennis Burton and Carlos Barbas. The
infectious molecularly cloned provirus ACH320.2A.1.2 was obtained through the NIBSC AIDS Reagent Project (United Kingdom) from
Hanneke Schuitemaker. We thank Dave Holley for technical assistance,
Joan Strange for DNA sequencing services (The University of Montana M. J. Murdock Molecular Biology Facility), Richard Field
(Department of Chemistry) for valuable discussions, and Ed Walker and
Linda Griggs (Ribi ImmunoChem Research, Inc.) for flow
cytometry.
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