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J Virol. 1972 June; 9(6): 1059-1063
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Absence of Leukosis Virus Markers in Hamster Cells Transformed by Herpes Simplex Virus Type 2

¹ Department of Microbiology, College of Medicine, The Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, Pennsylvania 17033

ABSTRACT

Hamster cells which transformed after exposure to herpes simplex virus type 2 previously irradiated with ultraviolet light were tested for the presence of hamster leukosis viruses or their virus-specific antigens. Three techniques that were used did not detect the presence of either hamster C-type particles or antigens commonly associated with such structures. The implication of these findings to current concepts of virus oncology is discussed.