This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Qiu, J.
Right arrow Articles by Pintel, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Qiu, J.
Right arrow Articles by Pintel, D.

 Previous Article  |  Next Article 

Journal of Virology, November 2007, p. 12080-12085, Vol. 81, No. 21
0022-538X/07/$08.00+0     doi:10.1128/JVI.00815-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

The Transcription Profile of the Bocavirus Bovine Parvovirus Is Unlike Those of Previously Characterized Parvoviruses{triangledown}

Jianming Qiu,1* Fang Cheng,1 F. Brent Johnson,2 and David Pintel3

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas,1 Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah,2 Department of Molecular Microbiology and Immunology, Life Sciences Center, University of Missouri-Columbia, Columbia, Missouri3

Received 16 April 2007/ Accepted 13 August 2007

The Bocavirus bovine parvovirus generated a single pre-mRNA from a promoter at its left-hand end; however, the pattern of its alternative polyadenylation and splicing was different from that of other parvoviruses. A large left-hand-end open reading frame (ORF) encoded a nonstructural protein of approximately 95 kDa. An abundant, spliced, internally polyadenylated transcript encoded the viral NP1 protein from an ORF in the center of the genome. Transcripts encoding the capsid proteins were polyadenylated in the right-hand terminal palindrome. This is the first published transcription map of a member of the Bocavirus genus of the Parvovirinae.

* Corresponding author. Mailing address: Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Mail Stop 3029, 3901 Rainbow Blvd., Kansas City, KS 66160. Phone: (913) 588-4329. Fax: (913) 588-7295. E-mail: jqiu{at}kumc.edu

{triangledown} Published ahead of print on 22 August 2007.

Journal of Virology, November 2007, p. 12080-12085, Vol. 81, No. 21
0022-538X/07/$08.00+0     doi:10.1128/JVI.00815-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Dijkman, R., Koekkoek, S. M., Molenkamp, R., Schildgen, O., van der Hoek, L. (2009). Human Bocavirus Can Be Cultured in Differentiated Human Airway Epithelial Cells. J. Virol. 83: 7739-7748 [Abstract] [Full Text]  
  • Sun, Y., Chen, A. Y., Cheng, F., Guan, W., Johnson, F. B., Qiu, J. (2009). Molecular Characterization of Infectious Clones of the Minute Virus of Canines Reveals Unique Features of Bocaviruses. J. Virol. 83: 3956-3967 [Abstract] [Full Text]  
  • Nelson, C. D. S., Minkkinen, E., Bergkvist, M., Hoelzer, K., Fisher, M., Bothner, B., Parrish, C. R. (2008). Detecting Small Changes and Additional Peptides in the Canine Parvovirus Capsid Structure. J. Virol. 82: 10397-10407 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»