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Journal of Virology, October 2002, p. 10518-10523, Vol. 76, No. 20
0022-538X/02/$04.00+0     DOI: 10.1128/JVI.76.20.10518-10523.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Elevated Chemokine Responses Are Maintained in Lungs after Clearance of Viral Infection

Department of Epidemiology,¹ Division of Pediatric Infectious Diseases,² Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109,⁴ Division of Virology and Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom³

Received 27 March 2002/ Accepted 3 July 2002

We observed two patterns of chemokine expression in the lungs of mice infected with murine gammaherpesvirus 68: peaks of chemokine expression correlated with or occurred after the peak of viral gene expression. Chemokine expression remained elevated through 29 days postinfection.

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