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Journal of Virology, March 2001, p. 3053-3057, Vol. 75, No. 6
0022-538X/01/$04.00+0   DOI: 10.1128/JVI.75.6.3053-3057.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Discovery of a Novel Murine Type C Retrovirus by Data Mining

Lindell Bromham,1,* Francis Clark,2 and Jeff J. McKee3

Department of Zoology,1 Department of Mathematics,2 and Division of Veterinary Pathology and Anatomy,3 University of Queensland, Brisbane 4072, Australia

Received 7 September 2000/Accepted 20 December 2000

Analysis of genomic and expression data allows both identification and characterization of novel retroviruses. We describe a recombinant type C murine retrovirus, similar to the Mus dunni endogenous retrovirus, with VL30-like long terminal repeats and murine leukemia virus-like coding sequences. This virus is present in multiple copies in the mouse genome and expressed in a range of mouse tissues.

* Corresponding author. Mailing address: Department of Zoology, University of Queensland, Brisbane 4072, Australia. Phone: 61 7 3365 2491. Fax: 61 7 3365 1655. E-mail: LBromham{at}zoology.uq.edu.au.

Journal of Virology, March 2001, p. 3053-3057, Vol. 75, No. 6
0022-538X/01/$04.00+0   DOI: 10.1128/JVI.75.6.3053-3057.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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