JVI Figure table search 04
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yao, Y.
Right arrow Articles by Barclay, W. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yao, Y.
Right arrow Articles by Barclay, W. S.

 Previous Article  |  Next Article 

Journal of Virology, June 2001, p. 5410-5415, Vol. 75, No. 11
0022-538X/01/$04.00+0   DOI: 10.1128/JVI.75.11.5410-5415.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Sequences in Influenza A Virus PB2 Protein That Determine Productive Infection for an Avian Influenza Virus in Mouse and Human Cell Lines

Yongxiu Yao,1 Louise J. Mingay,2 John W. McCauley,3 and Wendy S. Barclay1,*

School of Animal and Microbial Sciences, University of Reading, Reading, Berkshire RG6 6AJ,1 Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE,2 and Institute for Animal Health, Compton Laboratory, Compton, Newbury, Berkshire RG20 7NN,3 United Kingdom

Received 23 October 2000/Accepted 20 February 2001

Reverse genetics was used to analyze the host range of two avian influenza viruses which differ in their ability to replicate in mouse and human cells in culture. Engineered viruses carrying sequences encoding amino acids 362 to 581 of PB2 from a host range variant productively infect mouse and human cells.

* Corresponding author. Mailing address: School of Animal and Microbial Sciences, University of Reading, P.O. Box 228, Reading, Berkshire RG6 6AJ, United Kingdom. Phone: 44-1189-316368. Fax: 44-1189-316671. E-mail: w.s.barclay{at}reading.ac.uk.

Journal of Virology, June 2001, p. 5410-5415, Vol. 75, No. 11
0022-538X/01/$04.00+0   DOI: 10.1128/JVI.75.11.5410-5415.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
J. Bacteriol. Mol. Cell. Biol. Microbiol. Mol. Biol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2001 by the American Society for Microbiology. All rights reserved.