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Journal of Virology, June 2001, p. 5352-5356, Vol. 75, No. 11
0022-538X/01/$04.00+0   DOI: 10.1128/JVI.75.11.5352-5356.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Characterization of the Infectious Salmon Anemia Virus Genomic Segment That Encodes the Putative Hemagglutinin

Espen Rimstad,1,* Siri Mjaaland,1 Michael Snow,2 Aase B. Mikalsen,1 and Carey O. Cunningham2

Department of Pharmacology, Microbiology and Food Hygiene, The Norwegian School of Veterinary Science, N-0033 Oslo, Norway,1 and FRS Marine Laboratory, Aberdeen AB11 9DB, United Kingdom2

Received 21 November 2000/Accepted 7 March 2001

The genomic segment encoding the putative hemagglutinin of infectious salmon anemia virus (ISAV) is described. Expression of the putative hemagglutinin in a salmon cell line demonstrated hemadsorptive properties of the protein for salmon erythrocytes. The polypeptide was recognized by an ISAV-specific monoclonal antibody. Nucleotide sequencing indicated the occurrence of a variable region in the hemagglutinin gene.

* Corresponding author. Mailing address: Norwegian School of Veterinary Science, P.O. Box 8146 Dep., N-0033 Oslo, Norway. Phone: 47 2296 4766. Fax: 47 2296 4818. E-mail: espen.rimstad{at}veths.no.

Journal of Virology, June 2001, p. 5352-5356, Vol. 75, No. 11
0022-538X/01/$04.00+0   DOI: 10.1128/JVI.75.11.5352-5356.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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