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Journal of Virology, March 2000, p. 2955-2959, Vol. 74, No. 6
Department of Virology and Immunology,
Southwest Regional Primate Research Center, Southwest Foundation for
Biomedical Research, San Antonio, Texas 78227,1
and International Center for Gibbon Studies, Santa Clarita,
California 913802
Received 26 August 1999/Accepted 16 December 1999
The recent isolation of a nonhuman primate hepadnavirus from woolly
monkeys prompted an examination of other primates for potentially new
hepadnaviruses. A serological analysis of 30 captive gibbons revealed
that 47% were positive for at least one marker of ongoing or previous
infection with a hepatitis B virus (HBV). The amino acid sequences of
the core and surface genes of human and gibbon virus isolates were very
similar. Phylogenetic analysis indicated that the gibbon isolates lie
within the human HBV family, indicating that these HBV isolates most
likely stem from infection of gibbons from a human source.
0022-538X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Hepadnavirus Infection in Captive Gibbons
*
Corresponding author. Mailing address: Department of
Virology and Immunology, Southwest Regional Primate Research Center, Southwest Foundation for Biomedical Research, 7620 N.W. Loop 410, San
Antonio, TX 78227. Phone: (210) 258-9445. Fax: (210) 670-3329. E-mail:
rlanford{at}icarus.sfbr.org.
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