Previous Article | Next Article ![]()
Journal of Virology, August 2000, p. 7694-7697, Vol. 74, No. 16
Partners AIDS Research Center, Massachusetts
General Hospital, Charlestown, Massachusetts
021291; Division of Infectious Diseases,
The Children's Hospital, Boston, Massachusetts
021152; and Nuffield Department of
Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United
Kingdom3
Received 3 April 2000/Accepted 17 May 2000
Respiratory syncytial virus (RSV) infection is a major cause of
morbidity in childhood worldwide. The first human RSV-specific cytotoxic T-lymphocyte epitope to be defined is described. This HLA
B7-restricted epitope in nucleoprotein (NP) was detectable in four
healthy, B7-positive adult subjects using B7-RSV-NP tetrameric complexes to stain CD8+ T cells.
0022-538X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Characterization of a Novel Respiratory Syncytial
Virus-Specific Human Cytotoxic T-Lymphocyte Epitope
*
Corresponding author. Mailing address: Partners AIDS
Research Center, Massachusetts General Hospital, 13th St., Bldg. 149, Rm. 5218, Charlestown, MA 02129. Phone: (617) 726-5787. Fax: (617) 726-5411. E-mail: goulder{at}helix.mgh.harvard.edu.
This article has been cited by other articles:
| J. Bacteriol. | Mol. Cell. Biol. | Microbiol. Mol. Biol. Rev. |
|---|
| Clin. Vaccine Immunol. | ALL ASM JOURNALS |
|---|