This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Worobey, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Worobey, M.

 Previous Article  |  Next Article 

Journal of Virology, August 2000, p. 7666-7670, Vol. 74, No. 16
0022-538X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Extensive Homologous Recombination among Widely Divergent TT Viruses

Michael Worobey*

Department of Zoology, University of Oxford, Oxford, United Kingdom

Received 29 December 1999/Accepted 24 May 2000

Analyses of a collection of full-length TT virus genomes showed nearly half of them to be recombinant. The results were highly significant and revealed homologous recombination both within and among genotypes, often involving extremely divergent lineages. Recombination breakpoints were significantly more common in the noncoding region of the TT virus genome than in the coding region.


* Mailing address: Department of Zoology, University of Oxford, South Parks Rd., Oxford OX1 3PS, United Kingdom. Phone: 44 (0)1865 271273. Fax: 44 (0)1865 310447. E-mail: michael.worobey{at}zoo.ox.ac.uk.


Journal of Virology, August 2000, p. 7666-7670, Vol. 74, No. 16
0022-538X/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.



This article has been cited by other articles:

  • van der Walt, E., Rybicki, E. P., Varsani, A., Polston, J. E., Billharz, R., Donaldson, L., Monjane, A. L., Martin, D. P. (2009). Rapid host adaptation by extensive recombination. J. Gen. Virol. 90: 734-746 [Abstract] [Full Text]  
  • Leppik, L., Gunst, K., Lehtinen, M., Dillner, J., Streker, K., de Villiers, E.-M. (2007). In Vivo and In Vitro Intragenomic Rearrangement of TT Viruses. J. Virol. 81: 9346-9356 [Abstract] [Full Text]  
  • Hu, Y.-W., Al-Moslih, M. I., Al Ali, M. T., Khameneh, S. R., Perkins, H., Diaz-Mitoma, F., Roy, J. N., Uzicanin, S., Brown, E. G. (2005). Molecular Detection Method for All Known Genotypes of TT Virus (TTV) and TTV-Like Viruses in Thalassemia Patients and Healthy Individuals. J. Clin. Microbiol. 43: 3747-3754 [Full Text]  
  • Niel, C., Diniz-Mendes, L., Devalle, S. (2005). Rolling-circle amplification of Torque teno virus (TTV) complete genomes from human and swine sera and identification of a novel swine TTV genogroup. J. Gen. Virol. 86: 1343-1347 [Abstract] [Full Text]  
  • Jelcic, I., Hotz-Wagenblatt, A., Hunziker, A., zur Hausen, H., de Villiers, E.-M. (2004). Isolation of Multiple TT Virus Genotypes from Spleen Biopsy Tissue from a Hodgkin's Disease Patient: Genome Reorganization and Diversity in the Hypervariable Region. J. Virol. 78: 7498-7507 [Abstract] [Full Text]  
  • Barnett, O. E., Worobey, M., Holmes, E. C., Cooper, A. (2004). DETECTION OF TT VIRUS AMONG CHIMPANZEES IN THE WILD USING A NONINVASIVE TECHNIQUE. J Wildl Dis 40: 230-237 [Abstract] [Full Text]  
  • Ohshima, K., Yamaguchi, Y., Hirota, R., Hamamoto, T., Tomimura, K., Tan, Z., Sano, T., Azuhata, F., Walsh, J. A., Fletcher, J., Chen, J., Gera, A., Gibbs, A. (2002). Molecular evolution of Turnip mosaic virus: evidence of host adaptation, genetic recombination and geographical spread. J. Gen. Virol. 83: 1511-1521 [Abstract] [Full Text]  
  • Kakkola, L., Hedman, K., Vanrobaeys, H., Hedman, L., Soderlund-Venermo, M. (2002). Cloning and sequencing of TT virus genotype 6 and expression of antigenic open reading frame 2 proteins. J. Gen. Virol. 83: 979-990 [Abstract] [Full Text]  
  • Biagini, P., Gallian, P., Attoui, H., Touinssi, M., Cantaloube, J.-F., de Micco, P., de Lamballerie, X. (2001). Genetic analysis of full-length genomes and subgenomic sequences of TT virus-like mini virus human isolates. J. Gen. Virol. 82: 379-383 [Abstract] [Full Text]  
  • Bendinelli, M., Pistello, M., Maggi, F., Fornai, C., Freer, G., Vatteroni, M. L. (2001). Molecular Properties, Biology, and Clinical Implications of TT Virus, a Recently Identified Widespread Infectious Agent of Humans. Clin. Microbiol. Rev. 14: 98-113 [Abstract] [Full Text]