This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Beer, B. E.
Right arrow Articles by Hirsch, V. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Beer, B. E.
Right arrow Articles by Hirsch, V. M.

 Previous Article  |  Next Article 

Journal of Virology, September 1999, p. 7734-7744, Vol. 73, No. 9
0022-538X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Simian Immunodeficiency Virus (SIV) from Sun-Tailed Monkeys (Cercopithecus solatus): Evidence for Host-Dependent Evolution of SIV within the C. lhoesti Superspecies

Brigitte E. Beer,1 Elizabeth Bailes,2 Robert Goeken,1 George Dapolito,1 Cheik Coulibaly,3 Stephen G. Norley,3 Reinhard Kurth,3 Jean-Pierre Gautier,4 Annie Gautier-Hion,4 Dominique Vallet,4 Paul M. Sharp,2 and Vanessa M. Hirsch1,*

Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 208521; Institute of Genetics, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, United Kingdom2; Paul-Ehrlich-Institute, 63225 Langen, Germany3; and UMR 6552 (CNRS), Station Biologique, 35380 Paimpont, France4

Received 16 March 1999/Accepted 27 May 1999

Recently we reported the characterization of simian immunodeficiency virus (SIVlhoest) from a central African l'hoest monkey (Cercopithecus lhoesti lhoesti) that revealed a distant relationship to SIV isolated from a mandrill (SIVmnd). The present report describes a novel SIV (SIVsun) isolated from a healthy, wild-caught sun-tailed monkey (Cercopithecus lhoesti solatus), another member of the l'hoest superspecies. SIVsun replicated in a variety of human T-cell lines and in peripheral blood mononuclear cells of macaques (Macaca spp.) and patas monkeys (Erythrocebus patas). A full-length infectious clone of SIVsun was derived, and genetic analysis revealed that SIVsun was most closely related to SIVlhoest, with an amino acid identity of 71% in Gag, 73% in Pol, and 67% in Env. This degree of similarity is reminiscent of that observed between SIVagm isolates from vervet, grivet, and tantalus species of African green monkeys. The close relationship between SIVsun and SIVlhoest, despite their geographically distinct habitats, is consistent with evolution from a common ancestor, providing further evidence for the ancient nature of the primate lentivirus family. In addition, this observation leads us to suggest that the SIVmnd lineage should be designated the SIVlhoest lineage.

* Corresponding author. Mailing address: LMM, NIAID, NIH, 12441 Parklawn Dr., Rockville, MD 20852. Phone: (301) 496-2976. Fax: (301) 480-2618. E-mail: vhirsch{at}nih.gov.

Journal of Virology, September 1999, p. 7734-7744, Vol. 73, No. 9
0022-538X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Siegismund, C. S., Hohn, O., Kurth, R., Norley, S. (2009). Enhanced T- and B-cell responses to simian immunodeficiency virus (SIV)agm, SIVmac and human immunodeficiency virus type 1 Gag DNA immunization and identification of novel T-cell epitopes in mice via codon optimization. J. Gen. Virol. 90: 2513-2518 [Abstract] [Full Text]  
  • Souquiere, S., Onanga, R., Makuwa, M., Pandrea, I., Ngari, P., Rouquet, P., Bourry, O., Kazanji, M., Apetrei, C., Simon, F., Roques, P. (2009). Simian immunodeficiency virus types 1 and 2 (SIV mnd 1 and 2) have different pathogenic potentials in rhesus macaques upon experimental cross-species transmission. J. Gen. Virol. 90: 488-499 [Abstract] [Full Text]  
  • Liegeois, F., Lafay, B., Formenty, P., Locatelli, S., Courgnaud, V., Delaporte, E., Peeters, M. (2009). Full-Length Genome Characterization of a Novel Simian Immunodeficiency Virus Lineage (SIVolc) from Olive Colobus (Procolobus verus) and New SIVwrcPbb Strains from Western Red Colobus (Piliocolobus badius badius) from the Tai Forest in Ivory Coast. J. Virol. 83: 428-439 [Abstract] [Full Text]  
  • VandeWoude, S., Apetrei, C. (2006). Going Wild: Lessons from Naturally Occurring T-Lymphotropic Lentiviruses. Clin. Microbiol. Rev. 19: 728-762 [Abstract] [Full Text]  
  • Chen, J., Powell, D., Hu, W.-S. (2006). High Frequency of Genetic Recombination Is a Common Feature of Primate Lentivirus Replication. J. Virol. 80: 9651-9658 [Abstract] [Full Text]  
  • Onanga, R., Souquiere, S., Makuwa, M., Mouinga-Ondeme, A., Simon, F., Apetrei, C., Roques, P. (2006). Primary Simian Immunodeficiency Virus SIVmnd-2 Infection in Mandrills (Mandrillus sphinx).. J. Virol. 80: 3301-3309 [Abstract] [Full Text]  
  • Beer, B. E., Brown, C. R., Whitted, S., Goldstein, S., Goeken, R., Plishka, R., Buckler-White, A., Hirsch, V. M. (2005). Immunodeficiency in the Absence of High Viral Load in Pig-Tailed Macaques Infected with Simian Immunodeficiency Virus SIVsun or SIVlhoest. J. Virol. 79: 14044-14056 [Abstract] [Full Text]  
  • Takemura, T., Ekwalanga, M., Bikandou, B., Ido, E., Yamaguchi-Kabata, Y., Ohkura, S., Harada, H., Takehisa, J., Ichimura, H., Parra, H.-J., Nende, M., Mubwo, E., Sepole, M., Hayami, M., Miura, T. (2005). A novel simian immunodeficiency virus from black mangabey (Lophocebus aterrimus) in the Democratic Republic of Congo. J. Gen. Virol. 86: 1967-1971 [Abstract] [Full Text]  
  • Troyer, J. L., Pecon-Slattery, J., Roelke, M. E., Johnson, W., VandeWoude, S., Vazquez-Salat, N., Brown, M., Frank, L., Woodroffe, R., Winterbach, C., Winterbach, H., Hemson, G., Bush, M., Alexander, K. A., Revilla, E., O'Brien, S. J. (2005). Seroprevalence and Genomic Divergence of Circulating Strains of Feline Immunodeficiency Virus among Felidae and Hyaenidae Species. J. Virol. 79: 8282-8294 [Abstract] [Full Text]  
  • Dazza, M.-C., Ekwalanga, M., Nende, M., Shamamba, K. B., Bitshi, P., Paraskevis, D., Saragosti, S. (2005). Characterization of a Novel vpu-Harboring Simian Immunodeficiency Virus from a Dent's Mona Monkey (Cercopithecus mona denti). J. Virol. 79: 8560-8571 [Abstract] [Full Text]  
  • Sharp, P. M., Shaw, G. M., Hahn, B. H. (2005). Simian Immunodeficiency Virus Infection of Chimpanzees. J. Virol. 79: 3891-3902 [Full Text]  
  • Apetrei, C., Metzger, M. J., Richardson, D., Ling, B., Telfer, P. T., Reed, P., Robertson, D. L., Marx, P. A. (2005). Detection and Partial Characterization of Simian Immunodeficiency Virus SIVsm Strains from Bush Meat Samples from Rural Sierra Leone. J. Virol. 79: 2631-2636 [Abstract] [Full Text]  
  • Ndongmo, C. B., Switzer, W. M., Pau, C. P., Zeh, C., Schaefer, A., Pieniazek, D., Folks, T. M., Kalish, M. L. (2004). New Multiple Antigenic Peptide-Based Enzyme Immunoassay for Detection of Simian Immunodeficiency Virus Infection in Nonhuman Primates and Humans. J. Clin. Microbiol. 42: 5161-5169 [Abstract] [Full Text]  
  • Gaddis, N. C., Sheehy, A. M., Ahmad, K. M., Swanson, C. M., Bishop, K. N., Beer, B. E., Marx, P. A., Gao, F., Bibollet-Ruche, F., Hahn, B. H., Malim, M. H. (2004). Further Investigation of Simian Immunodeficiency Virus Vif Function in Human Cells. J. Virol. 78: 12041-12046 [Abstract] [Full Text]  
  • Bibollet-Ruche, F., Bailes, E., Gao, F., Pourrut, X., Barlow, K. L., Clewley, J. P., Mwenda, J. M., Langat, D. K., Chege, G. K., McClure, H. M., Mpoudi-Ngole, E., Delaporte, E., Peeters, M., Shaw, G. M., Sharp, P. M., Hahn, B. H. (2004). New Simian Immunodeficiency Virus Infecting De Brazza's Monkeys (Cercopithecus neglectus): Evidence for a Cercopithecus Monkey Virus Clade. J. Virol. 78: 7748-7762 [Abstract] [Full Text]  
  • Jackson, A. P., Charleston, M. A. (2004). A Cophylogenetic Perspective of RNA-Virus Evolution. Mol Biol Evol 21: 45-57 [Abstract] [Full Text]  
  • Courgnaud, V., Abela, B., Pourrut, X., Mpoudi-Ngole, E., Loul, S., Delaporte, E., Peeters, M. (2003). Identification of a New Simian Immunodeficiency Virus Lineage with a vpu Gene Present among Different Cercopithecus Monkeys (C. mona, C. cephus, and C. nictitans) from Cameroon. J. Virol. 77: 12523-12534 [Abstract] [Full Text]  
  • Salemi, M., De Oliveira, T., Courgnaud, V., Moulton, V., Holland, B., Cassol, S., Switzer, W. M., Vandamme, A.-M. (2003). Mosaic Genomes of the Six Major Primate Lentivirus Lineages Revealed by Phylogenetic Analyses. J. Virol. 77: 7202-7213 [Abstract] [Full Text]  
  • Barlow, K. L., Ajao, A. O., Clewley, J. P. (2003). Characterization of a Novel Simian Immunodeficiency Virus (SIVmonNG1) Genome Sequence from a Mona Monkey (Cercopithecus mona). J. Virol. 77: 6879-6888 [Abstract] [Full Text]  
  • Hu, J., Switzer, W. M., Foley, B. T., Robertson, D. L., Goeken, R. M., Korber, B. T., Hirsch, V. M., Beer, B. E. (2003). Characterization and Comparison of Recombinant Simian Immunodeficiency Virus from Drill (Mandrillus leucophaeus) and Mandrill (Mandrillus sphinx) Isolates. J. Virol. 77: 4867-4880 [Abstract] [Full Text]  
  • Ling, B., Santiago, M. L., Meleth, S., Gormus, B., McClure, H. M., Apetrei, C., Hahn, B. H., Marx, P. A. (2003). Noninvasive Detection of New Simian Immunodeficiency Virus Lineages in Captive Sooty Mangabeys: Ability To Amplify Virion RNA from Fecal Samples Correlates with Viral Load in Plasma. J. Virol. 77: 2214-2226 [Abstract] [Full Text]  
  • Courgnaud, V., Formenty, P., Akoua-Koffi, C., Noe, R., Boesch, C., Delaporte, E., Peeters, M. (2002). Partial Molecular Characterization of Two Simian Immunodeficiency Viruses (SIV) from African Colobids: SIVwrc from Western Red Colobus (Piliocolobus badius) and SIVolc from Olive Colobus (Procolobus verus). J. Virol. 77: 744-748 [Abstract] [Full Text]  
  • Onanga, R., Kornfeld, C., Pandrea, I., Estaquier, J., Souquiere, S., Rouquet, P., Mavoungou, V. P., Bourry, O., M'Boup, S., Barre-Sinoussi, F., Simon, F., Apetrei, C., Roques, P., Muller-Trutwin, M. C. (2002). High Levels of Viral Replication Contrast with Only Transient Changes in CD4+ and CD8+ Cell Numbers during the Early Phase of Experimental Infection with Simian Immunodeficiency Virus SIVmnd-1 in Mandrillus sphinx. J. Virol. 76: 10256-10263 [Abstract] [Full Text]  
  • Courgnaud, V., Salemi, M., Pourrut, X., Mpoudi-Ngole, E., Abela, B., Auzel, P., Bibollet-Ruche, F., Hahn, B., Vandamme, A.-M., Delaporte, E., Peeters, M. (2002). Characterization of a Novel Simian Immunodeficiency Virus with a vpu Gene from Greater Spot-Nosed Monkeys (Cercopithecus nictitans) Provides New Insights into Simian/Human Immunodeficiency Virus Phylogeny. J. Virol. 76: 8298-8309 [Abstract] [Full Text]  
  • Beer, B. E., Foley, B. T., Kuiken, C. L., Tooze, Z., Goeken, R. M., Brown, C. R., Hu, J., Claire, M. St., Korber, B. T., Hirsch, V. M. (2001). Characterization of Novel Simian Immunodeficiency Viruses from Red-Capped Mangabeys from Nigeria (SIVrcmNG409 and -NG411). J. Virol. 75: 12014-12027 [Abstract] [Full Text]  
  • Souquiere, S., Bibollet-Ruche, F., Robertson, D. L., Makuwa, M., Apetrei, C., Onanga, R., Kornfeld, C., Plantier, J.-C., Gao, F., Abernethy, K., White, L. J. T., Karesh, W., Telfer, P., Wickings, E. J., Mauclere, P., Marx, P. A., Barre-Sinoussi, F., Hahn, B. H., Muller-Trutwin, M. C., Simon, F. (2001). Wild Mandrillus sphinx Are Carriers of Two Types of Lentivirus. J. Virol. 75: 7086-7096 [Abstract] [Full Text]  
  • Broussard, S. R., Staprans, S. I., White, R., Whitehead, E. M., Feinberg, M. B., Allan, J. S. (2001). Simian Immunodeficiency Virus Replicates to High Levels in Naturally Infected African Green Monkeys without Inducing Immunologic or Neurologic Disease. J. Virol. 75: 2262-2275 [Abstract] [Full Text]  
  • Courgnaud, V., Pourrut, X., Bibollet-Ruche, F., Mpoudi-Ngole, E., Bourgeois, A., Delaporte, E., Peeters, M. (2001). Characterization of a Novel Simian Immunodeficiency Virus from Guereza Colobus Monkeys (Colobus guereza) in Cameroon: a New Lineage in the Nonhuman Primate Lentivirus Family. J. Virol. 75: 857-866 [Abstract] [Full Text]  
  • Goldstein, S., Ourmanov, I., Brown, C. R., Beer, B. E., Elkins, W. R., Plishka, R., Buckler-White, A., Hirsch, V. M. (2000). Wide Range of Viral Load in Healthy African Green Monkeys Naturally Infected with Simian Immunodeficiency Virus. J. Virol. 74: 11744-11753 [Abstract] [Full Text]  
  • Diop, O. M., Gueye, A., Dias-Tavares, M., Kornfeld, C., Faye, A., Ave, P., Huerre, M., Corbet, S., Barre-Sinoussi, F., Müller-Trutwin, M. C. (2000). High Levels of Viral Replication during Primary Simian Immunodeficiency Virus SIVagm Infection Are Rapidly and Strongly Controlled in African Green Monkeys. J. Virol. 74: 7538-7547 [Abstract] [Full Text]  
  • Beer, B. E., Bailes, E., Dapolito, G., Campbell, B. J., Goeken, R. M., Axthelm, M. K., Markham, P. D., Bernard, J., Zagury, D., Franchini, G., Sharp, P. M., Hirsch, V. M. (2000). Patterns of Genomic Sequence Diversity among Their Simian Immunodeficiency Viruses Suggest that L'Hoest Monkeys (Cercopithecus lhoesti) Are a Natural Lentivirus Reservoir. J. Virol. 74: 3892-3898 [Abstract] [Full Text]  
  • Hahn, B. H., Shaw, G. M., De, K. M., Cock, , Sharp, P. M. (2000). AIDS as a Zoonosis: Scientific and Public Health Implications. Science 287: 607-614 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»