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Journal of Virology, September 1998, p. 7685-7687, Vol. 72, No. 9
0022-538X/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

CrFK Feline Kidney Cells Produce an RD114-Like Endogenous Virus That Can Package Murine Leukemia Virus-Based Vectors

Jörg G. Baumann,1,2 Walter H. Günzburg,1,2,* and Brian Salmons3

Institute of Virology, University of Veterinary Sciences, A-1210 Vienna, Austria,1 and Institute of Molecular Virology, GSF-Research Center for Environment and Health, D-85758 Oberschleissheim,2 and Bavarian Nordic Research Institute, D-80807 Munich,3 Germany

Received 20 April 1998/Accepted 8 June 1998

The feline kidney cell line CrFK is used extensively for viral infectivity assays and for study of the biology of various retroviruses and derived vectors. We demonstrate the production of an endogenous, RD114-like, infectious retrovirus from CrFK cells. This virus also is shown to efficiently package Moloney murine leukemia virus vectors.

* Corresponding author. Mailing address: Institute of Virology, University of Veterinary Sciences, Josef-Baumann-Gasse 1, A-1210 Vienna, Austria. Phone: 43-1-25077-2301. Fax: 43-1-25077-2390. E-mail: walter.guenzburg{at}vu-wien.ac.at.

Journal of Virology, September 1998, p. 7685-7687, Vol. 72, No. 9
0022-538X/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.




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