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J Virol, May 1998, p. 4537-4540, Vol. 72, No. 5
Unité d'Oncologie Virale, Institut
Pasteur, 75724 Paris Cedex 15, France
Received 29 January 1997/Accepted 15 December 1997
We have investigated the molecular evidence in favor of the
transmission of human immunodeficiency virus (HIV) from an HIV-infected surgeon to one of his patients. After PCR amplification, the
env and gag sequences from the viral genome
were cloned and sequenced. Phylogenetic analysis revealed that the
viral sequences derived from the surgeon and his patient are closely
related, which strongly suggests that nosocomial transmission occurred.
In addition, these viral sequences belong to group M of HIV type 1 but
are divergent from the reference sequences of the known subtypes.
0022-538X/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
Molecular Evidence for Nosocomial Transmission of Human
Immunodeficiency Virus from a Surgeon to One of His
Patients
*
Corresponding author. Mailing address: Institut
Pasteur, Unité d'Oncologie Virale, 28, rue du Dr. Roux,
75724 Paris Cedex 15, France. Phone: 1-40-61-31-31. Fax:
1-40-61-34-65. E-mail: ablancha{at}pasteur.fr.
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