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Journal of Virology, December 1998, p. 10305-10309, Vol. 72, No. 12
0022-538X/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
A Novel Simian Immunodeficiency Virus (SIVdrl)
pol Sequence from the Drill Monkey, Mandrillus
leucophaeus
J. P.
Clewley,1,*
J. C. M.
Lewis,2
D. W. G.
Brown,1 and
E. L.
Gadsby3
Virus Reference Division, Central Public
Health Laboratory, London,1 and
International Zoo Veterinary Group,
Keighley,2 United Kingdom, and
Drill
Rehabilitation and Breeding Center, Calabar, Nigeria3
Received 24 April 1998/Accepted 10 September 1998
The drill monkey has been shown by serology and PCR to harbor a
unique simian immunodeficiency virus (SIVdrl). A pol
sequence, amplified from uncultured peripheral blood cells, is most
closely related to the equivalent SIV sequences from the red-capped
mangabey (SIVrcm), the sabaeus African green monkey (SIVagmSAB), and
the chimpanzee (SIVcpz) and to the human immunodeficiency virus type 1 (HIV-1) sequence of humans. It is as yet unclear whether SIVdrl has a
mosaic genome like SIVrcm and SIVagmSAB, is a member of the
SIVcpz/HIV-1 lineage, or represents a novel primate lentivirus lineage.
*
Corresponding author. Mailing address: Virus Reference
Division, Central Public Health Laboratory, 61 Colindale Ave., London NW9 5HT, United Kingdom. Phone: 44 181 200 4400, ext. 3245. Fax: 44 181 200 1569. E-mail: jclewley{at}hgmp.mrc.ac.uk.
Journal of Virology, December 1998, p. 10305-10309, Vol. 72, No. 12
0022-538X/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
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