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J Virol. 1971 May; 7(5): 687-689
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Purification of the Sabin Strain of Poliovirus Type I Through Treatment with Sarkozyl

Marc Fiszman, Danielle Bucchini and Marc Girard

Unité de Physiologie des Virus, Institut de Recherches sur le Cancer, B.P. No. 8, 94—Villejuif, France

ABSTRACT

Sodium dodecyl sulfate was found to aggregate virions from the Sabin Lsc2ab strain of poliovirus type 1. Aggregation was prevented by high ionic strength buffers. A procedure is described for the rapid purification of the virus through the use of sarkozyl.

J Virol. 1971 May; 7(5): 687-689
Copyright © 1971 American Society for Microbiology. All Rights Reserved.





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J. Bacteriol. Mol. Cell. Biol. Microbiol. Mol. Biol. Rev.
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Copyright © 1971 by the American Society for Microbiology. All rights reserved.