This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shafren, D. R.
Right arrow Articles by Barry, R. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shafren, D. R.
Right arrow Articles by Barry, R. D.

 Previous Article  |  Next Article 

J. Virol., Jun 1995, 3873-3877, Vol 69, No. 6
Copyright © 1995, American Society for Microbiology

Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment

DR Shafren, RC Bates, MV Agrez, RL Herd, GF Burns and RD Barry
Department of Microbiology, Faculty of Medicine, University of Newcastle, New South Wales, Australia.

Receptor binding and subsequent cell-mediated internalization or disassembly are the initial steps in virus replication. Cell surface molecules that participate in this process are the primary determinants of virus tissue tropism. Monoclonal antibody blockade, immunoprecipitation, and DNA transfection were used to identify decay accelerating factor as a major cell attachment receptor for coxsackieviruses B1, B3, and B5. However, expression of human decay acceleration factor on the surface of nonpermissive murine fibroblasts led only to virus attachment without subsequent replication, and it was concluded that an additional cellular cofactor(s) is required to facilitate cell entry and subsequent replication.


This article has been cited by other articles:

  • Patel, K. P., Coyne, C. B., Bergelson, J. M. (2009). Dynamin- and Lipid Raft-Dependent Entry of Decay-Accelerating Factor (DAF)-Binding and Non-DAF-Binding Coxsackieviruses into Nonpolarized Cells. J. Virol. 83: 11064-11077 [Abstract] [Full Text]  
  • Fumagalli, M., Cagliani, R., Pozzoli, U., Riva, S., Comi, G. P., Menozzi, G., Bresolin, N., Sironi, M. (2009). Widespread balancing selection and pathogen-driven selection at blood group antigen genes. Genome Res 19: 199-212 [Abstract] [Full Text]  
  • Krautkramer, E., Zeier, M. (2008). Hantavirus Causing Hemorrhagic Fever with Renal Syndrome Enters from the Apical Surface and Requires Decay-Accelerating Factor (DAF/CD55). J. Virol. 82: 4257-4264 [Abstract] [Full Text]  
  • Nilsson, E. C., Jamshidi, F., Johansson, S. M. C., Oberste, M. S., Arnberg, N. (2008). Sialic Acid Is a Cellular Receptor for Coxsackievirus A24 Variant, an Emerging Virus with Pandemic Potential. J. Virol. 82: 3061-3068 [Abstract] [Full Text]  
  • Hafenstein, S., Bowman, V. D., Chipman, P. R., Kelly, C. M. B., Lin, F., Medof, M. E., Rossmann, M. G. (2007). Interaction of Decay-Accelerating Factor with Coxsackievirus B3. J. Virol. 81: 12927-12935 [Abstract] [Full Text]  
  • Johansson, C., Jonsson, M., Marttila, M., Persson, D., Fan, X.-L., Skog, J., Frangsmyr, L., Wadell, G., Arnberg, N. (2007). Adenoviruses Use Lactoferrin as a Bridge for CAR-Independent Binding to and Infection of Epithelial Cells. J. Virol. 81: 954-963 [Abstract] [Full Text]  
  • Garcia-Valladares, I, Atisha-Fregoso, Y, Richaud-Patin, Y, Jakez-Ocampo, J, Soto-Vega, E, Elias-Lopez, D, Carrillo-Maravilla, E, Cabiedes, J, Ruiz-Arguelles, A, Llorente, L (2006). Diminished expression of complement regulatory proteins (CD55 and CD59) in lymphocytes from systemic lupus erythematosus patients with lymphopenia. Lupus 15: 600-605 [Abstract]  
  • Lim, B.-K., Choi, J.-H., Nam, J.-H., Gil, C.-O., Shin, J.-O., Yun, S.-H., Kim, D.-K., Jeon, E.-S. (2006). Virus receptor trap neutralizes coxsackievirus in experimental murine viral myocarditis. Cardiovasc Res 71: 517-526 [Abstract] [Full Text]  
  • Pasch, A., Frey, F. J. (2006). Coxsackie B viruses and the kidney--a neglected topic. Nephrol Dial Transplant 21: 1184-1187 [Abstract] [Full Text]  
  • Goodfellow, I. G., Evans, D. J., Blom, A. M., Kerrigan, D., Miners, J. S., Morgan, B. P., Spiller, O. B. (2005). Inhibition of Coxsackie B Virus Infection by Soluble Forms of Its Receptors: Binding Affinities, Altered Particle Formation, and Competition with Cellular Receptors. J. Virol. 79: 12016-12024 [Abstract] [Full Text]  
  • Jimenez-Clavero, M. A., Escribano-Romero, E., Ley, V., Spiller, O. B. (2005). More recent swine vesicular disease virus isolates retain binding to coxsackie-adenovirus receptor, but have lost the ability to bind human decay-accelerating factor (CD55). J. Gen. Virol. 86: 1369-1377 [Abstract] [Full Text]  
  • Servin, A. L. (2005). Pathogenesis of Afa/Dr Diffusely Adhering Escherichia coli. Clin. Microbiol. Rev. 18: 264-292 [Abstract] [Full Text]  
  • Milstone, A. M., Petrella, J., Sanchez, M. D., Mahmud, M., Whitbeck, J. C., Bergelson, J. M. (2005). Interaction with Coxsackievirus and Adenovirus Receptor, but Not with Decay-Accelerating Factor (DAF), Induces A-Particle Formation in a DAF-Binding Coxsackievirus B3 Isolate. J. Virol. 79: 655-660 [Abstract] [Full Text]  
  • Shen, Y., Xu, W., Chu, Y.-W., Wang, Y., Liu, Q.-S., Xiong, S.-D. (2004). Coxsackievirus Group B Type 3 Infection Upregulates Expression of Monocyte Chemoattractant Protein 1 in Cardiac Myocytes, Which Leads to Enhanced Migration of Mononuclear Cells in Viral Myocarditis. J. Virol. 78: 12548-12556 [Abstract] [Full Text]  
  • Johansson, E. S., Xing, L., Cheng, R. H., Shafren, D. R. (2004). Enhanced Cellular Receptor Usage by a Bioselected Variant of Coxsackievirus A21. J. Virol. 78: 12603-12612 [Abstract] [Full Text]  
  • Newcombe, N. G., Beagley, L. G., Christiansen, D., Loveland, B. E., Johansson, E. S., Beagley, K. W., Barry, R. D., Shafren, D. R. (2004). Novel Role for Decay-Accelerating Factor in Coxsackievirus A21-Mediated Cell Infectivity. J. Virol. 78: 12677-12682 [Abstract] [Full Text]  
  • Hudault, S., Spiller, O. B., Morgan, B. P., Servin, A. L. (2004). Human Diffusely Adhering Escherichia coli Expressing Afa/Dr Adhesins That Use Human CD55 (Decay-Accelerating Factor) as a Receptor Does Not Bind the Rodent and Pig Analogues of CD55. Infect. Immun. 72: 4859-4863 [Abstract] [Full Text]  
  • Dorner, A., Xiong, D., Couch, K., Yajima, T., Knowlton, K. U. (2004). Alternatively Spliced Soluble Coxsackie-adenovirus Receptors Inhibit Coxsackievirus Infection. J. Biol. Chem. 279: 18497-18503 [Abstract] [Full Text]  
  • Williams, D. T., Chaudhry, Y., Goodfellow, I. G., Lea, S., Evans, D. J. (2004). Interactions of decay-accelerating factor (DAF) with haemagglutinating human enteroviruses: utilizing variation in primate DAF to map virus binding sites. J. Gen. Virol. 85: 731-738 [Abstract] [Full Text]  
  • Bhella, D., Goodfellow, I. G., Roversi, P., Pettigrew, D., Chaudhry, Y., Evans, D. J., Lea, S. M. (2004). The Structure of Echovirus Type 12 Bound to a Two-domain Fragment of Its Cellular Attachment Protein Decay-accelerating Factor (CD 55). J. Biol. Chem. 279: 8325-8332 [Abstract] [Full Text]  
  • Newcombe, N. G., Johansson, E. S., Au, G., Lindberg, A. M., Barry, R. D., Shafren, D. R. (2004). Enterovirus Capsid Interactions with Decay-Accelerating Factor Mediate Lytic Cell Infection. J. Virol. 78: 1431-1439 [Abstract] [Full Text]  
  • Newcombe, N. G., Andersson, P., Johansson, E. S., Au, G. G., Lindberg, A. M., Barry, R. D., Shafren, D. R. (2003). Cellular receptor interactions of C-cluster human group A coxsackieviruses. J. Gen. Virol. 84: 3041-3050 [Abstract] [Full Text]  
  • Zautner, A. E., Korner, U., Henke, A., Badorff, C., Schmidtke, M. (2003). Heparan Sulfates and Coxsackievirus-Adenovirus Receptor: Each One Mediates Coxsackievirus B3 PD Infection. J. Virol. 77: 10071-10077 [Abstract] [Full Text]  
  • Poller, W., Fechner, H., Noutsias, M., Tschoepe, C., Pauschinger, M., Schultheiss, H.-P. (2002). The molecular basis of cardiotropic viral infections. Eur Heart J Suppl 4: I18-I30 [Abstract]  
  • Liu, P., Lee, P., Fuse, K., Nian, M. (2002). Molecular pathophysiological mechanisms in virus infected host myocardium. Eur Heart J Suppl 4: I37-I41 [Abstract]  
  • Alexander, D. A., Dimock, K. (2002). Sialic Acid Functions in Enterovirus 70 Binding and Infection. J. Virol. 76: 11265-11272 [Abstract] [Full Text]  
  • Shieh, J. T. C., Bergelson, J. M. (2002). Interaction with Decay-Accelerating Factor Facilitates Coxsackievirus B Infection of Polarized Epithelial Cells. J. Virol. 76: 9474-9480 [Abstract] [Full Text]  
  • Luo, H., Yanagawa, B., Zhang, J., Luo, Z., Zhang, M., Esfandiarei, M., Carthy, C., Wilson, J. E., Yang, D., McManus, B. M. (2002). Coxsackievirus B3 Replication Is Reduced by Inhibition of the Extracellular Signal-Regulated Kinase (ERK) Signaling Pathway. J. Virol. 76: 3365-3373 [Abstract] [Full Text]  
  • Huang, Y. T., Yam, P., Yan, H., Sun, Y. (2002). Engineered BGMK Cells for Sensitive and Rapid Detection of Enteroviruses. J. Clin. Microbiol. 40: 366-371 [Abstract] [Full Text]  
  • Spiller, O. B., Goodfellow, I. G., Evans, D. J., Hinchliffe, S. J., Morgan, B. P. (2002). Coxsackie B viruses that use human DAF as a receptor infect pig cells via pig CAR and do not use pig DAF. J. Gen. Virol. 83: 45-52 [Abstract] [Full Text]  
  • Leippert, M., Pfaff, E. (2001). Foot-and-mouth disease virus can utilize the C-terminal extension of coxsackievirus A9 VP1 for cell infection. J. Gen. Virol. 82: 1703-1711 [Abstract] [Full Text]  
  • Goodfellow, I. G., Sioofy, A. B., Powell, R. M., Evans, D. J. (2001). Echoviruses Bind Heparan Sulfate at the Cell Surface. J. Virol. 75: 4918-4921 [Abstract] [Full Text]  
  • Tamura, M., Natori, K., Kobayashi, M., Miyamura, T., Takeda, N. (2000). Interaction of Recombinant Norwalk Virus Particles with the 105-Kilodalton Cellular Binding Protein, a Candidate Receptor Molecule for Virus Attachment. J. Virol. 74: 11589-11597 [Abstract] [Full Text]  
  • Triantafilou, K., Triantafilou, M., Takada, Y., Fernandez, N. (2000). Human Parechovirus 1 Utilizes Integrins alpha vbeta 3 and alpha vbeta 1 as Receptors. J. Virol. 74: 5856-5862 [Abstract] [Full Text]  
  • Guignot, J., Peiffer, I., Bernet-Camard, M.-F., Lublin, D. M., Carnoy, C., Moseley, S. L., Servin, A. L. (2000). Recruitment of CD55 and CD66e Brush Border-Associated Glycosylphosphatidylinositol-Anchored Proteins by Members of the Afa/Dr Diffusely Adhering Family of Escherichia coli That Infect the Human Polarized Intestinal Caco-2/TC7 Cells. Infect. Immun. 68: 3554-3563 [Abstract] [Full Text]  
  • Schneider-Schaulies, J. (2000). Cellular receptors for viruses: links to tropism and pathogenesis. J. Gen. Virol. 81: 1413-1429 [Full Text]  
  • Goodfellow, I. G., Powell, R. M., Ward, T., Spiller, O. B., Almond, J. W., Evans, D. J. (2000). Echovirus infection of rhabdomyosarcoma cells is inhibited by antiserum to the complement control protein CD59. J. Gen. Virol. 81: 1393-1401 [Abstract] [Full Text]  
  • Shafren, D. R., Dorahy, D. J., Thorne, R. F., Barry, R. D. (2000). Cytoplasmic interactions between decay-accelerating factor and intercellular adhesion molecule-1 are not required for coxsackievirus A21 cell infection. J. Gen. Virol. 81: 889-894 [Abstract] [Full Text]  
  • Selvarangan, R., Goluszko, P., Popov, V., Singhal, J., Pham, T., Lublin, D. M., Nowicki, S., Nowicki, B. (2000). Role of Decay-Accelerating Factor Domains and Anchorage in Internalization of Dr-Fimbriated Escherichia coli. Infect. Immun. 68: 1391-1399 [Abstract] [Full Text]  
  • Liu, P. P., Opavsky, M. A. (2000). Viral Myocarditis : Receptors That Bridge the Cardiovascular With the Immune System?. Circ. Res. 86: 253-254 [Full Text]  
  • Powell, R. M., Ward, T., Goodfellow, I., Almond, J. W., Evans, D. J. (1999). Mapping the binding domains on decay accelerating factor (DAF) for haemagglutinating enteroviruses: implications for the evolution of a DAF-binding phenotype. J. Gen. Virol. 80: 3145-3152 [Abstract] [Full Text]  
  • Pasch, A., Küpper, J.-H., Wolde, A., Kandolf, R., Selinka, H.-C. (1999). Comparative analysis of virus-host cell interactions of haemagglutinating and non-haemagglutinating strains of coxsackievirus B3. J. Gen. Virol. 80: 3153-3158 [Abstract] [Full Text]  
  • Triantafilou, M., Triantafilou, K., Wilson, K. M., Takada, Y., Fernandez, N., Stanway, G. (1999). Involvement of {beta}2-microglobulin and integrin {alpha}v{beta}3 molecules in the coxsackievirus A9 infectious cycle. J. Gen. Virol. 80: 2591-2600 [Abstract] [Full Text]  
  • Mena, I., Perry, C. M., Harkins, S., Rodriguez, F., Gebhard, J., Whitton, J. L. (1999). The Role of B Lymphocytes in Coxsackievirus B3 Infection. Am. J. Pathol. 155: 1205-1215 [Abstract] [Full Text]  
  • Shafren, D. R., Gardner, J., Mann, V. H., Antalis, T. M., Suhrbier, A. (1999). Picornavirus Receptor Down-Regulation by Plasminogen Activator Inhibitor Type 2. J. Virol. 73: 7193-7198 [Abstract] [Full Text]  
  • Sánchez, C. M., Izeta, A., Sánchez-Morgado, J. M., Alonso, S., Sola, I., Balasch, M., Plana-Durán, J., Enjuanes, L. (1999). Targeted Recombination Demonstrates that the Spike Gene of Transmissible Gastroenteritis Coronavirus Is a Determinant of Its Enteric Tropism and Virulence. J. Virol. 73: 7607-7618 [Abstract] [Full Text]  
  • Carson, S. D., Hobbs, J. T., Tracy, S. M., Chapman, N. M. (1999). Expression of the Coxsackievirus and Adenovirus Receptor in Cultured Human Umbilical Vein Endothelial Cells: Regulation in Response to Cell Density. J. Virol. 73: 7077-7079 [Abstract] [Full Text]  
  • Vuorinen, T, Vainionpaa, R, Heino, J, Hyypia, T (1999). Enterovirus receptors and virus replication in human leukocytes. J. Gen. Virol. 80: 921-927 [Abstract]  
  • Wang, X., Bergelson, J. M. (1999). Coxsackievirus and Adenovirus Receptor Cytoplasmic and Transmembrane Domains Are Not Essential for Coxsackievirus and Adenovirus Infection. J. Virol. 73: 2559-2562 [Abstract] [Full Text]  
  • Karnauchow, T. M., Dawe, S., Lublin, D. M., Dimock, K. (1998). Short Consensus Repeat Domain 1 of Decay-Accelerating Factor Is Required for Enterovirus 70 Binding. J. Virol. 72: 9380-9383 [Abstract] [Full Text]  
  • Shafren, D. R. (1998). Viral Cell Entry Induced by Cross-Linked Decay-Accelerating Factor. J. Virol. 72: 9407-9412 [Abstract] [Full Text]  
  • Ward, T., Powell, R. M., Pipkin, P. A., Evans, D. J., Minor, P. D., Almond, J. W. (1998). Role for beta 2-Microglobulin in Echovirus Infection of Rhabdomyosarcoma Cells. J. Virol. 72: 5360-5365 [Abstract] [Full Text]  
  • Neff, S., Sa-Carvalho, D., Rieder, E., Mason, P. W., Blystone, S. D., Brown, E. J., Baxt, B. (1998). Foot-and-Mouth Disease Virus Virulent for Cattle Utilizes the Integrin alpha vbeta 3 as Its Receptor. J. Virol. 72: 3587-3594 [Abstract] [Full Text]  
  • Shafren, D. R., Dorahy, D. J., Thorne, R. F., Kinoshita, T., Barry, R. D., Burns, G. F. (1998). Antibody Binding to Individual Short Consensus Repeats of Decay-Accelerating Factor Enhances Enterovirus Cell Attachment and Infectivity. J. Immunol. 160: 2318-2323 [Abstract] [Full Text]  
  • Muir, P., Kammerer, U., Korn, K., Mulders, M. N., Poyry, T., Weissbrich, B., Kandolf, R., Cleator, G. M., van Loon, A. M. (1998). Molecular Typing of Enteroviruses: Current Status and Future Requirements. Clin. Microbiol. Rev. 11: 202-227 [Abstract] [Full Text]  
  • Pulli, T., Koivunen, E., Hyypia, T. (1997). Cell-surface Interactions of Echovirus 22. J. Biol. Chem. 272: 21176-21180 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»