This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lewis, P F
Right arrow Articles by Emerman, M
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lewis, P F
Right arrow Articles by Emerman, M

 Previous Article  |  Next Article 

J Virol. 1994 January; 68(1): 510-516

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus.

P F Lewis and M Emerman

Department of Pediatrics, University of Washington, Seattle.

ABSTRACT

The human immunodeficiency virus productively infects and integrates into cells that have been arrested in the cell cycle with either gamma irradiation or aphidicolin. Integration by oncoretroviruses such as the murine leukemia virus (MuLV), on the other hand, depends on cell proliferation. Although the entire cell cycle is not necessary for MuLV infection, it is essential that the infected cells pass through mitosis. The long terminal repeat circle junction, a marker for nuclear entry, is first observed in MuLV-infected cells immediately after mitosis. These results suggest that mitosis is necessary for nuclear entry of MuLV, but not human immunodeficiency virus, unintegrated proviral DNA.

J Virol. 1994 January; 68(1): 510-516




This article has been cited by other articles:

  • Scheller, E.L., Krebsbach, P.H. (2009). Gene Therapy: Design and Prospects for Craniofacial Regeneration. JDR 88: 585-596 [Abstract] [Full Text]  
  • Qi, M., Yang, R., Aiken, C. (2008). Cyclophilin A-Dependent Restriction of Human Immunodeficiency Virus Type 1 Capsid Mutants for Infection of Nondividing Cells. J. Virol. 82: 12001-12008 [Abstract] [Full Text]  
  • Porter, C. C., DeGregori, J. (2008). Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection. Blood 112: 4466-4474 [Abstract] [Full Text]  
  • Faulkner, R. L., Jang, M.-H., Liu, X.-B., Duan, X., Sailor, K. A., Kim, J. Y., Ge, S., Jones, E. G., Ming, G.-l., Song, H., Cheng, H.-J. (2008). Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain. Proc. Natl. Acad. Sci. USA 105: 14157-14162 [Abstract] [Full Text]  
  • Skasko, M., Kim, B. (2008). Compensatory Role of Human Immunodeficiency Virus Central Polypurine Tract Sequence in Kinetically Disrupted Reverse Transcription. J. Virol. 82: 7716-7720 [Abstract] [Full Text]  
  • Katzourakis, A., Pereira, V., Tristem, M. (2007). Effects of Recombination Rate on Human Endogenous Retrovirus Fixation and Persistence. J. Virol. 81: 10712-10717 [Abstract] [Full Text]  
  • Shun, M.-C., Daigle, J. E., Vandegraaff, N., Engelman, A. (2007). Wild-Type Levels of Human Immunodeficiency Virus Type 1 Infectivity in the Absence of Cellular Emerin Protein. J. Virol. 81: 166-172 [Abstract] [Full Text]  
  • Singhal, P. K., Rajendra Kumar, P., Subba Rao, M. R. K., Mahalingam, S. (2006). Nuclear Export of Simian Immunodeficiency Virus Vpx Protein. J. Virol. 80: 12271-12282 [Abstract] [Full Text]  
  • Ackman, J. B., Siddiqi, F., Walikonis, R. S., LoTurco, J. J. (2006). Fusion of microglia with pyramidal neurons after retroviral infection.. J. Neurosci. 26: 11413-11422 [Abstract] [Full Text]  
  • Operario, D. J., Balakrishnan, M., Bambara, R. A., Kim, B. (2006). Reduced dNTP Interaction of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Promotes Strand Transfer. J. Biol. Chem. 281: 32113-32121 [Abstract] [Full Text]  
  • Anderson, J. L., Campbell, E. M., Wu, X., Vandegraaff, N., Engelman, A., Hope, T. J. (2006). Proteasome Inhibition Reveals that a Functional Preintegration Complex Intermediate Can Be Generated during Restriction by Diverse TRIM5 Proteins. J. Virol. 80: 9754-9760 [Abstract] [Full Text]  
  • Yu, J. H., Schaffer, D. V. (2006). High-throughput, library-based selection of a murine leukemia virus variant to infect nondividing cells.. J. Virol. 80: 8981-8988 [Abstract] [Full Text]  
  • Jamburuthugoda, V. K., Chugh, P., Kim, B. (2006). Modification of Human Immunodeficiency Virus Type 1 Reverse Transcriptase to Target Cells with Elevated Cellular dNTP Concentrations. J. Biol. Chem. 281: 13388-13395 [Abstract] [Full Text]  
  • Chen, B., Nelson, D. M., Sadovsky, Y. (2006). N-Myc Down-regulated Gene 1 Modulates the Response of Term Human Trophoblasts to Hypoxic Injury. J. Biol. Chem. 281: 2764-2772 [Abstract] [Full Text]  
  • Jarrosson-Wuilleme, L., Goujon, C., Bernaud, J., Rigal, D., Darlix, J.-L., Cimarelli, A. (2006). Transduction of Nondividing Human Macrophages with Gammaretrovirus-Derived Vectors. J. Virol. 80: 1152-1159 [Abstract] [Full Text]  
  • Yueh, A., Leung, J., Bhattacharyya, S., Perrone, L. A., de los Santos, K., Pu, S.-y., Goff, S. P. (2006). Interaction of Moloney Murine Leukemia Virus Capsid with Ubc9 and PIASy Mediates SUMO-1 Addition Required Early in Infection. J. Virol. 80: 342-352 [Abstract] [Full Text]  
  • Singhal, P. K., Kumar, P. R., Rao, M. R. K. S., Kyasani, M., Mahalingam, S. (2006). Simian Immunodeficiency Virus Vpx Is Imported into the Nucleus via Importin Alpha-Dependent and -Independent Pathways. J. Virol. 80: 526-536 [Abstract] [Full Text]  
  • Song, H., Kempermann, G., Wadiche, L. O., Zhao, C., Schinder, A. F., Bischofberger, J. (2005). New Neurons in the Adult Mammalian Brain: Synaptogenesis and Functional Integration. J. Neurosci. 25: 10366-10368 [Full Text]  
  • Haffar, O., Dubrovsky, L., Lowe, R., Berro, R., Kashanchi, F., Godden, J., Vanpouille, C., Bajorath, J., Bukrinsky, M. (2005). Oxadiazols: a New Class of Rationally Designed Anti-Human Immunodeficiency Virus Compounds Targeting the Nuclear Localization Signal of the Viral Matrix Protein. J. Virol. 79: 13028-13036 [Abstract] [Full Text]  
  • Zielske, S. P., Stevenson, M. (2005). Importin 7 May Be Dispensable for Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus Infection of Primary Macrophages. J. Virol. 79: 11541-11546 [Abstract] [Full Text]  
  • Wang, J. M., Johnston, P. B., Ball, B. G., Brinton, R. D. (2005). The Neurosteroid Allopregnanolone Promotes Proliferation of Rodent and Human Neural Progenitor Cells and Regulates Cell-Cycle Gene and Protein Expression. J. Neurosci. 25: 4706-4718 [Abstract] [Full Text]  
  • Busschots, K., Vercammen, J., Emiliani, S., Benarous, R., Engelborghs, Y., Christ, F., Debyser, Z. (2005). The Interaction of LEDGF/p75 with Integrase Is Lentivirus-specific and Promotes DNA Binding. J. Biol. Chem. 280: 17841-17847 [Abstract] [Full Text]  
  • Wu, X., Li, Y., Crise, B., Burgess, S. M., Munroe, D. J. (2005). Weak Palindromic Consensus Sequences Are a Common Feature Found at the Integration Target Sites of Many Retroviruses. J. Virol. 79: 5211-5214 [Abstract] [Full Text]  
  • Skasko, M., Weiss, K. K., Reynolds, H. M., Jamburuthugoda, V., Lee, K., Kim, B. (2005). Mechanistic Differences in RNA-dependent DNA Polymerization and Fidelity between Murine Leukemia Virus and HIV-1 Reverse Transcriptases. J. Biol. Chem. 280: 12190-12200 [Abstract] [Full Text]  
  • Rajendra Kumar, P., Singhal, P. K., Subba Rao, M. R. K., Mahalingam, S. (2005). Phosphorylation by MAPK Regulates Simian Immunodeficiency Virus Vpx Protein Nuclear Import and Virus Infectivity. J. Biol. Chem. 280: 8553-8563 [Abstract] [Full Text]  
  • Buholzer, C. F., Arrighi, J.-F., Abraham, S., Piguet, V., Capponi, A. M., Casal, A. J. (2005). Chicken Ovalbumin Upstream Promoter-Transcription Factor Is a Negative Regulator of Steroidogenesis in Bovine Adrenal Glomerulosa Cells. Mol. Endocrinol. 19: 65-75 [Abstract] [Full Text]  
  • Diamond, T. L., Roshal, M., Jamburuthugoda, V. K., Reynolds, H. M., Merriam, A. R., Lee, K. Y., Balakrishnan, M., Bambara, R. A., Planelles, V., Dewhurst, S., Kim, B. (2004). Macrophage Tropism of HIV-1 Depends on Efficient Cellular dNTP Utilization by Reverse Transcriptase. J. Biol. Chem. 279: 51545-51553 [Abstract] [Full Text]  
  • Ikeda, T., Nishitsuji, H., Zhou, X., Nara, N., Ohashi, T., Kannagi, M., Masuda, T. (2004). Evaluation of the Functional Involvement of Human Immunodeficiency Virus Type 1 Integrase in Nuclear Import of Viral cDNA during Acute Infection. J. Virol. 78: 11563-11573 [Abstract] [Full Text]  
  • Iordanskiy, S., Zhao, Y., DiMarzio, P., Agostini, I., Dubrovsky, L., Bukrinsky, M. (2004). Heat-shock protein 70 exerts opposing effects on Vpr-dependent and Vpr-independent HIV-1 replication in macrophages. Blood 104: 1867-1872 [Abstract] [Full Text]  
  • Llano, M., Vanegas, M., Fregoso, O., Saenz, D., Chung, S., Peretz, M., Poeschla, E. M. (2004). LEDGF/p75 Determines Cellular Trafficking of Diverse Lentiviral but Not Murine Oncoretroviral Integrase Proteins and Is a Component of Functional Lentiviral Preintegration Complexes. J. Virol. 78: 9524-9537 [Abstract] [Full Text]  
  • Maertens, G., Cherepanov, P., Debyser, Z., Engelborghs, Y., Engelman, A. (2004). Identification and Characterization of a Functional Nuclear Localization Signal in the HIV-1 Integrase Interactor LEDGF/p75. J. Biol. Chem. 279: 33421-33429 [Abstract] [Full Text]  
  • Mitta, B., Weber, C. C., Rimann, M., Fussenegger, M. (2004). Design and in vivo characterization of self-inactivating human and non-human lentiviral expression vectors engineered for streptogramin-adjustable transgene expression. Nucleic Acids Res 32: e106-e106 [Abstract] [Full Text]  
  • Serhan, F., Penaud, M., Petit, C., Leste-Lasserre, T., Trajcevski, S., Klatzmann, D., Duisit, G., Sonigo, P., Moullier, P. (2004). Early Detection of a Two-Long-Terminal-Repeat Junction Molecule in the Cytoplasm of Recombinant Murine Leukemia Virus-Infected Cells. J. Virol. 78: 6190-6199 [Abstract] [Full Text]  
  • Wotherspoon, S., Dolnikov, A., Symonds, G., Nordon, R. (2004). Susceptibility of Cell Populations to Transduction by Retroviral Vectors. J. Virol. 78: 5097-5102 [Abstract] [Full Text]  
  • Horn, P. A., Keyser, K. A., Peterson, L. J., Neff, T., Thomasson, B. M., Thompson, J., Kiem, H.-P. (2004). Efficient lentiviral gene transfer to canine repopulating cells using an overnight transduction protocol. Blood 103: 3710-3716 [Abstract] [Full Text]  
  • Greger, J. G., Katz, R. A., Taganov, K., Rall, G. F., Skalka, A. M. (2004). Transduction of Terminally Differentiated Neurons by Avian Sarcoma Virus. J. Virol. 78: 4902-4906 [Abstract] [Full Text]  
  • Ao, Z., Yao, X., Cohen, E. A. (2004). Assessment of the Role of the Central DNA Flap in Human Immunodeficiency Virus Type 1 Replication by Using a Single-Cycle Replication System. J. Virol. 78: 3170-3177 [Abstract] [Full Text]  
  • Trobridge, G., Russell, D. W. (2004). Cell Cycle Requirements for Transduction by Foamy Virus Vectors Compared to Those of Oncovirus and Lentivirus Vectors. J. Virol. 78: 2327-2335 [Abstract] [Full Text]  
  • Morris, J. C., Conerly, M., Thomasson, B., Storek, J., Riddell, S. R., Kiem, H.-P. (2004). Induction of cytotoxic T-lymphocyte responses to enhanced green and yellow fluorescent proteins after myeloablative conditioning. Blood 103: 492-499 [Abstract] [Full Text]  
  • Katz, R. A., Greger, J. G., Boimel, P., Skalka, A. M. (2003). Human Immunodeficiency Virus Type 1 DNA Nuclear Import and Integration Are Mitosis Independent in Cycling Cells. J. Virol. 77: 13412-13417 [Abstract] [Full Text]  
  • Lewis, B. C., Klimstra, D. S., Varmus, H. E. (2003). The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer. Genes Dev. 17: 3127-3138 [Abstract] [Full Text]  
  • Dolnikov, A., Wotherspoon, S., Millington, M., Symonds, G. (2003). Retrovirus vector production and transduction: modulation by the cell cycle. J. Gen. Virol. 84: 3131-3141 [Abstract] [Full Text]  
  • Chilov, D., Fux, C., Joch, H., Fussenegger, M. (2003). Identification of a novel proliferation-inducing determinant using lentiviral expression cloning. Nucleic Acids Res 31: e113-e113 [Abstract] [Full Text]  
  • Maertens, G., Cherepanov, P., Pluymers, W., Busschots, K., De Clercq, E., Debyser, Z., Engelborghs, Y. (2003). LEDGF/p75 Is Essential for Nuclear and Chromosomal Targeting of HIV-1 Integrase in Human Cells. J. Biol. Chem. 278: 33528-33539 [Abstract] [Full Text]  
  • Sherman, M. P., de Noronha, C. M. C., Eckstein, L. A., Hataye, J., Mundt, P., Williams, S. A. F., Neidleman, J. A., Goldsmith, M. A., Greene, W. C. (2003). Nuclear Export of Vpr Is Required for Efficient Replication of Human Immunodeficiency Virus Type 1 in Tissue Macrophages. J. Virol. 77: 7582-7589 [Abstract] [Full Text]  
  • Ramezani, A., Hawley, T. S., Hawley, R. G. (2003). Performance- and safety-enhanced lentiviral vectors containing the human interferon-{beta} scaffold attachment region and the chicken {beta}-globin insulator. Blood 101: 4717-4724 [Abstract] [Full Text]  
  • Fleury, S., Simeoni, E., Zuppinger, C., Deglon, N., von Segesser, L. K., Kappenberger, L., Vassalli, G. (2003). Multiply Attenuated, Self-Inactivating Lentiviral Vectors Efficiently Deliver and Express Genes for Extended Periods of Time in Adult Rat Cardiomyocytes In Vivo. Circulation 107: 2375-2382 [Abstract] [Full Text]  
  • Woodward, C. L., Wang, Y., Dixon, W. J., Htun, H., Chow, S. A. (2003). Subcellular Localization of Feline Immunodeficiency Virus Integrase and Mapping of Its Karyophilic Determinant. J. Virol. 77: 4516-4527 [Abstract] [Full Text]  
  • Bruland, T., Lavik, L. A. S., Dai, H. Y., Dalen, A. (2003). A glucocorticoid response element in the LTR U3 region of Friend murine leukaemia virus variant FIS-2 enhances virus production in vitro and is a major determinant for sex differences in susceptibility to FIS-2 infection in vivo. J. Gen. Virol. 84: 907-916 [Abstract] [Full Text]  
  • Yueh, A., Goff, S. P. (2003). Phosphorylated Serine Residues and an Arginine-Rich Domain of the Moloney Murine Leukemia Virus p12 Protein Are Required for Early Events of Viral Infection. J. Virol. 77: 1820-1829 [Abstract] [Full Text]  
  • Roesler, J., Brenner, S., Bukovsky, A. A., Whiting-Theobald, N., Dull, T., Kelly, M., Civin, C. I., Malech, H. L. (2002). Third-generation, self-inactivating gp91phox lentivector corrects the oxidase defect in NOD/SCID mouse-repopulating peripheral blood-mobilized CD34+ cells from patients with X-linked chronic granulomatous disease. Blood 100: 4381-4390 [Abstract] [Full Text]  
  • Loewen, N., Bahler, C., Teo, W.-l., Whitwam, T., Peretz, M., Xu, R., Fautsch, M. P., Johnson, D. H., Poeschla, E. M. (2002). Preservation of Aqueous Outflow Facility after Second-Generation FIV Vector-Mediated Expression of Marker Genes in Anterior Segments of Human Eyes. IOVS 43: 3686-3690 [Abstract] [Full Text]  
  • Horn, P. A., Topp, M. S., Morris, J. C., Riddell, S. R., Kiem, H.-P. (2002). Highly efficient gene transfer into baboon marrow repopulating cells using GALV-pseudotype oncoretroviral vectors produced by human packaging cells. Blood 100: 3960-3967 [Abstract] [Full Text]  
  • Limon, A., Nakajima, N., Lu, R., Ghory, H. Z., Engelman, A. (2002). Wild-Type Levels of Nuclear Localization and Human Immunodeficiency Virus Type 1 Replication in the Absence of the Central DNA Flap. J. Virol. 76: 12078-12086 [Abstract] [Full Text]  
  • Dvorin, J. D., Bell, P., Maul, G. G., Yamashita, M., Emerman, M., Malim, M. H. (2002). Reassessment of the Roles of Integrase and the Central DNA Flap in Human Immunodeficiency Virus Type 1 Nuclear Import. J. Virol. 76: 12087-12096 [Abstract] [Full Text]  
  • Limon, A., Devroe, E., Lu, R., Ghory, H. Z., Silver, P. A., Engelman, A. (2002). Nuclear Localization of Human Immunodeficiency Virus Type 1 Preintegration Complexes (PICs): V165A and R166A Are Pleiotropic Integrase Mutants Primarily Defective for Integration, Not PIC Nuclear Import. J. Virol. 76: 10598-10607 [Abstract] [Full Text]  
  • Yuan, B., Fassati, A., Yueh, A., Goff, S. P. (2002). Characterization of Moloney Murine Leukemia Virus p12 Mutants Blocked during Early Events of Infection. J. Virol. 76: 10801-10810 [Abstract] [Full Text]  
  • VandenDriessche, T., Thorrez, L., Naldini, L., Follenzi, A., Moons, L., Berneman, Z., Collen, D., Chuah, M. K. L. (2002). Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo. Blood 100: 813-822 [Abstract] [Full Text]  
  • Werner, S., Hindmarsh, P., Napirei, M., Vogel-Bachmayr, K., Wohrl, B. M. (2002). Subcellular Localization and Integration Activities of Rous Sarcoma Virus Reverse Transcriptase. J. Virol. 76: 6205-6212 [Abstract] [Full Text]  
  • Katz, R. A., Greger, J. G., Darby, K., Boimel, P., Rall, G. F., Skalka, A. M. (2002). Transduction of Interphase Cells by Avian Sarcoma Virus. J. Virol. 76: 5422-5434 [Abstract] [Full Text]  
  • Eckstein, D. A., Sherman, M. P., Penn, M. L., Chin, P. S., De Noronha, C. M.C., Greene, W. C., Goldsmith, M. A. (2001). HIV-1 Vpr Enhances Viral Burden by Facilitating Infection of Tissue Macrophages but Not Nondividing CD4+ T Cells. JEM 194: 1407-1419 [Abstract] [Full Text]  
  • Lewis, B. C., Chinnasamy, N., Morgan, R. A., Varmus, H. E. (2001). Development of an Avian Leukosis-Sarcoma Virus Subgroup A Pseudotyped Lentiviral Vector. J. Virol. 75: 9339-9344 [Abstract] [Full Text]  
  • Whitwam, T., Peretz, M., Poeschla, E. (2001). Identification of a Central DNA Flap in Feline Immunodeficiency Virus. J. Virol. 75: 9407-9414 [Abstract] [Full Text]  
  • Hatziioannou, T., Goff, S. P. (2001). Infection of Nondividing Cells by Rous Sarcoma Virus. J. Virol. 75: 9526-9531 [Abstract] [Full Text]  
  • Wang, D., de la Fuente, C., Deng, L., Wang, L., Zilberman, I., Eadie, C., Healey, M., Stein, D., Denny, T., Harrison, L. E., Meijer, L., Kashanchi, F. (2001). Inhibition of Human Immunodeficiency Virus Type 1 Transcription by Chemical Cyclin-Dependent Kinase Inhibitors. J. Virol. 75: 7266-7279 [Abstract] [Full Text]  
  • Dirks, C., Miller, A. D. (2001). Many Nonmammalian Cells Exhibit Postentry Blocks to Transduction by Gammaretroviruses Pseudotyped with Various Viral Envelopes, Including Vesicular Stomatitis Virus G Glycoprotein. J. Virol. 75: 6375-6383 [Abstract] [Full Text]  
  • Kowolik, C. M., Hu, J., Yee, J.-K. (2001). Locus Control Region of the Human CD2 Gene in a Lentivirus Vector Confers Position-Independent Transgene Expression. J. Virol. 75: 4641-4648 [Abstract] [Full Text]  
  • An, D. S., Kung, S. K. P., Bonifacino, A., Wersto, R. P., Metzger, M. E., Agricola, B. A., Mao, S. H., Chen, I. S. Y., Donahue, R. E. (2001). Lentivirus Vector-Mediated Hematopoietic Stem Cell Gene Transfer of Common Gamma-Chain Cytokine Receptor in Rhesus Macaques. J. Virol. 75: 3547-3555 [Abstract] [Full Text]  
  • Fassati, A., Goff, S. P. (2001). Characterization of Intracellular Reverse Transcription Complexes of Human Immunodeficiency Virus Type 1. J. Virol. 75: 3626-3635 [Abstract] [Full Text]  
  • Berkowitz, R., Ilves, H., Lin, W. Y., Eckert, K., Coward, A., Tamaki, S., Veres, G., Plavec, I. (2001). Construction and Molecular Analysis of Gene Transfer Systems Derived from Bovine Immunodeficiency Virus. J. Virol. 75: 3371-3382 [Abstract] [Full Text]  
  • Wang, X., Lewis, D. E. (2001). CD86 expression correlates with amounts of HIV produced by macrophages in vitro. J. Leukoc. Biol. 69: 405-413 [Abstract] [Full Text]  
  • Van den Broeke, A., Cleuter, Y., Beskorwayne, T., Kerkhofs, P., Szynal, M., Bagnis, C., Burny, A., Griebel, P. (2001). CD154 Costimulated Ovine Primary B Cells, a Cell Culture System That Supports Productive Infection by Bovine Leukemia Virus. J. Virol. 75: 1095-1103 [Abstract] [Full Text]  
  • Sherman, M. P., de Noronha, C. M. C., Heusch, M. I., Greene, S., Greene, W. C. (2001). Nucleocytoplasmic Shuttling by Human Immunodeficiency Virus Type 1 Vpr. J. Virol. 75: 1522-1532 [Abstract] [Full Text]  
  • Mahalingam, S., Van Tine, B., Santiago, M. L., Gao, F., Shaw, G. M., Hahn, B. H. (2001). Functional Analysis of the Simian Immunodeficiency Virus Vpx Protein: Identification of Packaging Determinants and a Novel Nuclear Targeting Domain. J. Virol. 75: 362-374 [Abstract] [Full Text]  
  • Dyall, J., Latouche, J.-B., Schnell, S., Sadelain, M. (2001). Lentivirus-transduced human monocyte-derived dendritic cells efficiently stimulate antigen-specific cytotoxic T lymphocytes. Blood 97: 114-121 [Abstract] [Full Text]  
  • Gupta, K., Ott, D., Hope, T. J., Siliciano, R. F., Boeke, J. D. (2000). A Human Nuclear Shuttling Protein That Interacts with Human Immunodeficiency Virus Type 1 Matrix Is Packaged into Virions. J. Virol. 74: 11811-11824 [Abstract] [Full Text]  
  • Mikkola, H., Woods, N.-B., Sjögren, M., Helgadottir, H., Hamaguchi, I., Jacobsen, S.-E., Trono, D., Karlsson, S. (2000). Lentivirus Gene Transfer in Murine Hematopoietic Progenitor Cells Is Compromised by a Delay in Proviral Integration and Results in Transduction Mosaicism and Heterogeneous Gene Expression in Progeny Cells. J. Virol. 74: 11911-11918 [Abstract] [Full Text]  
  • Woods, N.-B., Fahlman, C., Mikkola, H., Hamaguchi, I., Olsson, K., Zufferey, R., Jacobsen, S. E., Trono, D., Karlsson, S. (2000). Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells. Blood 96: 3725-3733 [Abstract] [Full Text]  
  • Reiser, J., Lai, Z., Zhang, X.-Y., Brady, R. O. (2000). Development of Multigene and Regulated Lentivirus Vectors. J. Virol. 74: 10589-10599 [Abstract] [Full Text]  
  • Sharma, S., Miyanohara, A., Friedmann, T. (2000). Separable Mechanisms of Attachment and Cell Uptake during Retrovirus Infection. J. Virol. 74: 10790-10795 [Abstract] [Full Text]  
  • Salmon, P., Kindler, V., Ducrey, O., Chapuis, B., Zubler, R. H., Trono, D. (2000). High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors. Blood 96: 3392-3398 [Abstract] [Full Text]  
  • Mangeot, P.-E., Nègre, D., Dubois, B., Winter, A. J., Leissner, P., Mehtali, M., Kaiserlian, D., Cosset, F.-L., Darlix, J.-L. (2000). Development of Minimal Lentivirus Vectors Derived from Simian Immunodeficiency Virus (SIVmac251) and Their Use for Gene Transfer into Human Dendritic Cells. J. Virol. 74: 8307-8315 [Abstract] [Full Text]  
  • Zhu, T. (2000). HIV-1 genotypes in peripheral blood monocytes. J. Leukoc. Biol. 68: 338-344 [Abstract] [Full Text]  
  • Petit, C., Schwartz, O., Mammano, F. (2000). The Karyophilic Properties of Human Immunodeficiency Virus Type 1 Integrase Are Not Required for Nuclear Import of Proviral DNA. J. Virol. 74: 7119-7126 [Abstract] [Full Text]  
  • Kurian, K M, Watson, C J, Wyllie, A H (2000). Retroviral vectors. Mol. Pathol. 53: 173-176 [Abstract] [Full Text]  
  • Dardalhon, V., Jaleco, S., Rebouissou, C., Ferrand, C., Skander, N., Swainson, L., Tiberghien, P., Spits, H., Noraz, N., Taylor, N. (2000). Highly efficient gene transfer in naive human T cells with a murine leukemia virus-based vector. Blood 96: 885-893 [Abstract] [Full Text]  
  • Srinivasakumar, N., Schuening, F. (2000). Novel Tat-Encoding Bicistronic Human Immunodeficiency Virus Type 1-Based Gene Transfer Vectors for High-Level Transgene Expression. J. Virol. 74: 6659-6668 [Abstract] [Full Text]  
  • Pancio, H. A., Vander Heyden, N., Ratner, L. (2000). The C-Terminal Proline-Rich Tail of Human Immunodeficiency Virus Type 2 Vpx Is Necessary for Nuclear Localization of the Viral Preintegration Complex in Nondividing Cells. J. Virol. 74: 6162-6167 [Abstract] [Full Text]  
  • MacKenzie, K. L., Hackett, N. R., Crystal, R. G., Moore, M. A. S. (2000). Adenoviral vector-mediated gene transfer to primitive human hematopoietic progenitor cells: assessment of transduction and toxicity in long-term culture. Blood 96: 100-108 [Abstract] [Full Text]  
  • Buchschacher, G. L. Jr, Wong-Staal, F. (2000). Development of lentiviral vectors for gene therapy for human diseases. Blood 95: 2499-2504 [Abstract] [Full Text]  
  • Schiedlmeier, B., Kuhlcke, K., Eckert, H. G., Baum, C., Zeller, W. J., Fruehauf, S. (2000). Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice. Blood 95: 1237-1248 [Abstract] [Full Text]  
  • An, D. S., Wersto, R. P., Agricola, B. A., Metzger, M. E., Lu, S., Amado, R. G., Chen, I. S. Y., Donahue, R. E. (2000). Marking and Gene Expression by a Lentivirus Vector in Transplanted Human and Nonhuman Primate CD34+ Cells. J. Virol. 74: 1286-1295 [Abstract] [Full Text]  
  • Lieber, A., Kay, M. A., Li, Z.-Y. (2000). Nuclear Import of Moloney Murine Leukemia Virus DNA Mediated by Adenovirus Preterminal Protein Is Not Sufficient for Efficient Retroviral Transduction in Nondividing Cells. J. Virol. 74: 721-734 [Abstract] [Full Text]  
  • Fassati, A., Goff, S. P. (1999). Characterization of Intracellular Reverse Transcription Complexes of Moloney Murine Leukemia Virus. J. Virol. 73: 8919-8925 [Abstract] [Full Text]  
  • Srinivasakumar, N., Schuening, F. G. (1999). A Lentivirus Packaging System Based on Alternative RNA Transport Mechanisms To Express Helper and Gene Transfer Vector RNAs and Its Use To Study the Requirement of Accessory Proteins for Particle Formation and Gene Delivery. J. Virol. 73: 9589-9598 [Abstract] [Full Text]  
  • Buchschacher, G. L. Jr., Yu, L., Murai, F., Friedmann, T., Miyanohara, A. (1999). Association of Murine Leukemia Virus Pol with Virions, Independent of Gag-Pol Expression. J. Virol. 73: 9632-9637 [Abstract] [Full Text]  
  • Unutmaz, D., KewalRamani, V. N., Marmon, S., Littman, D. R. (1999). Cytokine Signals Are Sufficient for HIV-1 Infection of Resting Human T Lymphocytes. JEM 189: 1735-1746 [Abstract] [Full Text]  
  • Johnston, J. C., Gasmi, M., Lim, L. E., Elder, J. H., Yee, J.-K., Jolly, D. J., Campbell, K. P., Davidson, B. L., Sauter, S. L. (1999). Minimum Requirements for Efficient Transduction of Dividing and Nondividing Cells by Feline Immunodeficiency Virus Vectors. J. Virol. 73: 4991-5000 [Abstract] [Full Text]  
  • Petit, C., Schwartz, O., Mammano, F. (1999). Oligomerization within Virions and Subcellular Localization of Human Immunodeficiency Virus Type 1 Integrase. J. Virol. 73: 5079-5088 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»