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J Virol. 1992 March; 66(3): 1389-1393

LRV1 viral particles in Leishmania guyanensis contain double-stranded or single-stranded RNA.

R Weeks, R F Aline Jr, P J Myler and K Stuart

Seattle Biomedical Research Institute, Washington 98109-1651.

ABSTRACT

The 32-nm-diameter spherical viral particles found in the cytoplasm of Leishmania guyanensis CUMC1-1A sediment at 130S and have a buoyant density of approximately 1.4 g/ml in cesium chloride gradients. These particles contain a 5.3-kb double-stranded RNA, while single-stranded RNA that corresponds to the viral positive strand is associated with less-dense particles. These results suggest a conservative and sequential mode of LRV1 viral RNA replication that is exemplified by the ScV L-A virus of yeast.

J Virol. 1992 March; 66(3): 1389-1393






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J. Bacteriol. Mol. Cell. Biol. Microbiol. Mol. Biol. Rev.
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Copyright © 1992 by the American Society for Microbiology. All rights reserved.