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J Virol. 1987 August; 61(8): 2624-2626

Immunoglobulin A monoclonal antibodies protect against Sendai virus.

M B Mazanec, J G Nedrud and M E Lamm

ABSTRACT

Immunoglobulin A anti-Sendai virus HN protein monoclonal antibodies, generated via a mucosal immunization protocol, were shown to neutralize virus in vitro and, when passively administered to the mouse respiratory tract, to protect against Sendai virus in vivo. Thus, immunoglobulin A antibodies by themselves can protect against respiratory virus infection.

J Virol. 1987 August; 61(8): 2624-2626




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Copyright © 1987 by the American Society for Microbiology. All rights reserved.