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J Virol. 1987 June; 61(6): 1834-1841

Evidence that the sigma 1 protein of reovirus serotype 3 is a multimer.

R Bassel-Duby, M L Nibert, C J Homcy, B N Fields and D G Sawutz

ABSTRACT

In this report, we study the reovirus serotype 3 (strain Dearing) sigma 1 protein obtained from various sources: from Escherichia coli expressing sigma 1 protein, from reovirus-infected mouse L cells, and from purified reovirions. We demonstrate that the sigma 1 protein is a multimer in its undisrupted form and present biochemical evidence suggesting that the multimer is made up of four sigma 1 subunits.

J Virol. 1987 June; 61(6): 1834-1841




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