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J Virol. 1987 December; 61(12): 4043-4045

Frequent involvement of the fim-3 region in Friend murine leukemia virus-induced mouse myeloblastic leukemias.

D Bordereaux, S Fichelson, B Sola, P E Tambourin and S Gisselbrecht

Laboratoire Immunologie et Virologie des Tumeurs, Institut National de la Santé et de la Recherche Médicale, Paris, France.

ABSTRACT

fim-3 is a new proviral integration region involved in 23% (16 of 68) of Friend murine leukemia virus-induced myeloblastic leukemias. This region is distinct from 20 oncogenes and from putative oncogenes tested so far. Proviruses are integrated in a 16-kilobase region, always in the same orientation. No RNA expression of fim-3 was detected.


J Virol. 1987 December; 61(12): 4043-4045




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