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J Virol. 1987 November; 61(11): 3617-3620

Expression of envelope glycoproteins of human immunodeficiency virus by an insect virus vector.

S I Hu, S G Kosowski and K F Schaaf

Oncogen System Corporation, Seattle, Washington 98121.

ABSTRACT

The envelope gene of human immunodeficiency virus was inserted into the genome of an insect virus vector (Autographa californica nuclear polyhedrosis virus). Upon infection of tissue culture cells, this recombinant virus produced immunoreactive polypeptides related to the envelope glycoproteins of human immunodeficiency virus. Serological survey indicates such polypeptides would be of value as antigens in diagnostics for acquired immunodeficiency syndrome.


J Virol. 1987 November; 61(11): 3617-3620




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