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Electron Microscopic Observations on Virus-Like Particles Associated with SH Antigen

Department of Anatomy, New York Medical College, New York, New York 10029
Division of Gastroenterology, Department of Medicine, and Department of Pathology, Cornell University Medical College, New York, New York 10021
Laboratory of Virology, The New York Blood Center, New York, New York 10021

ABSTRACT

The structural aspects of SH antigen-containing particles were investigated. These studies confirmed the existence of a large spherical particle (ca. 43 nm) and smaller (ca. 20 nm) rod- and sphere-shaped particles. The large particle consists of an outer and inner membrane and a core of "nucleic acid" as seen by positive staining techniques. The outer membrane of the large particle appears to be similar to that of the 20-nm diameter spheres and rods known to possess the SH antigen.

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