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J Virol. 1970 October; 6(4): 556-558
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Quantitative Determination of Neuraminidase-Active Foci in Cell Monolayer Cultures Infected with Influenza or Newcastle Disease Virus

P. Palese, G. Bodo and H. Tuppy

Institut für Biochemie, University of Vienna, A-1090 Vienna, Austria
Arzneimittelforschung GmbH, A-1121 Vienna, Austria

ABSTRACT

A synthetic neuraminidase substrate [2-(3'-methoxyphenyl)-N-acetyl-{alpha}-neuraminic acid] was used to detect myxo- and paramyxovirus replication in tissue culture. This method allowed estimation of viral growth even in the absence of cytopathogenic effects.

J Virol. 1970 October; 6(4): 556-558
Copyright © 1970 American Society for Microbiology. All Rights Reserved.





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Copyright © 1970 by the American Society for Microbiology. All rights reserved.