This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Quintrell, N. A. Articles by McAuslan, B. R. Search for Related Content PubMed PubMed Citation Articles by Quintrell, N. A. Articles by McAuslan, B. R.

Inhibition of Poxvirus Replication by Streptovaricin

Roche Institute of Molecular Biology, Nutley, New Jersey 07110

ABSTRACT

A component of streptovaricin complex inhibits the replication of poxvirus. To be effective, the inhibitor must be introduced early in the replication cycle; it appears to inhibit early messenger ribonucleic acid synthesis by viral cores, thus interfering with all subsequent events. Neither of the two major components of the complex, streptovaricin A or C, was the active component.

¹ Department of Microbiology, University of California Medical Center, San Francisco, Calif. 94122.