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J Virol. 1986 April; 58(1): 220-222

Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis.

A Löve, R Rydbeck, G Utter, C Orvell, K Kristensson and E Norrby

ABSTRACT

A monoclonal antibody against the fusion (F) protein of mumps virus was found to confer marked protection in mumps virus-induced encephalitis. Almost total prevention of extensive brain necrosis was found. This study indicates that the virus F protein is directly involved in the pathogenesis of brain necrosis.

J Virol. 1986 April; 58(1): 220-222




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