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J Virol. 1985 December; 56(3): 1023-1026

Polyomavirus middle T protein encoded by a retrovirus transforms nonestablished chicken embryo cells.

P L Kaplan, S Simon and W Eckhart

ABSTRACT

A murine retrovirus encoding the middle T protein of polyomavirus infected and transformed nonestablished chicken embryo cells. The infected cultures formed colonies in soft agar-containing medium and released infectious transforming virus. Middle T protein expressed in the transformed chicken cells associated with p60c-src and, in immunoprecipitates, enhanced the tyrosine protein kinase activity of p60c-src.

J Virol. 1985 December; 56(3): 1023-1026






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