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 Previous Article

J Virol. 1985 November; 56(2): 651-654

Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines.

D Matteucci, M Paglianti, A M Giangregorio, M R Capobianchi, F Dianzani and M Bendinelli

ABSTRACT

Exposing human lymphoid cell lines to uncloned or recently cloned group B coxsackieviruses results in the frequent establishment of chronically infected cultures. Persistence is maintained by a carrier culture mechanism involving virus spread through the medium and replication among a minority of cells at any given time. These studies provide a model for persistence by highly cytocidal viruses.

J Virol. 1985 November; 56(2): 651-654




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