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J Virol. 1985 August; 55(2): 497-499

Expression of the x-lor gene of human T-cell leukemia virus I in Escherichia coli.

W C Goh, J Sodroski, C Rosen and W Haseltine

ABSTRACT

The 3'-terminal regions of the human T-cell leukemia virus I (HTLV-I) and HTLV-II genomes encode a novel gene product. We showed that expression of this region fused to the beta-galactosidase gene in bacteria produces a protein recognized by adult T-cell leukemia-lymphoma patient sera. Rabbit antibodies raised against this protein specifically precipitated the 42-kilodalton x-lor gene protein from HTLV-I-infected cells.

J Virol. 1985 August; 55(2): 497-499






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