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J Virol. 1985 January; 53(1): 335-339
A determinant of polyomavirus virulence enhances virus growth in cells of renal origin.
J B Bolen,
S E Fisher,
K Chowdhury,
T C Shan,
J E Williams,
C J Dawe and
M A Israel
ABSTRACT
We have identified a strain of polyomavirus, Py(L), which is unusual in causing acute morbidity and early death after inoculation of newborn mice. We determined that these animals died of kidney failure associated with extensive, virus-mediated destruction of renal tissue. Interestingly, the Py(L) strain infects baby mouse kidney cell cultures more efficiently than do other strains.
J Virol. 1985 January; 53(1): 335-339
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Copyright © 1985 by the American Society for Microbiology. All rights reserved.