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J Virol. 1984 June; 50(3): 954-956

Analysis of T antigen and viral DNA in mouse cells transformed by K virus, a nononcogenic murine papovavirus.

T Kanda and K K Takemoto

ABSTRACT

A tumorigenic line of mouse cells transformed by the nononcogenic murine K papovavirus was established and characterized. Tumor-bearing animals produced antibody specific for K virus-transformed cells; the K virus T antiserum did not react with polyomavirus-transformed cells. Immunoprecipitation of the T antigen in the transformed cells revealed large T antigen (molecular weight 84,000). About 10 to 15 copies of K virus DNA were found to be integrated in the cellular DNA.

J Virol. 1984 June; 50(3): 954-956




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