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J Virol. 1970 February; 5(2): 173-178
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Disruption of Adenovirus Type 7 by Lithium Iodide Resulting in the Release of Viral Deoxyribonucleic Acid

A. Robert Neurath, John T. Stasny and Benjamin A. Rubin

Department of Research and Development, Wyeth Laboratories, Inc., Philadelphia, Pennsylvania 19101

ABSTRACT

Adenovirus type 7 exposed to solutions of LiI was progressively converted into slower sedimenting deoxyribonucleic acid (DNA)-containing particles, and, ultimately, under proper conditions, DNA free or almost free from protein was released from the virus. The degree of viral degradation was dependent on the time of treatment, on the temperature, and on the concentration of the reagent.

J Virol. 1970 February; 5(2): 173-178
Copyright © 1970 American Society for Microbiology. All Rights Reserved.





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Copyright © 1970 by the American Society for Microbiology. All rights reserved.