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J Virol. 1984 February; 49(2): 579-582

Nucleotide sequence of the transforming gene of m1 murine sarcoma virus.

M A Brow, A Sen and J G Sutcliffe

ABSTRACT

The v-mosm1 nucleotide sequence codes for a protein that is 376 amino acids long. Although the N-terminus is homologous with that of the v-mos124 protein, the C-terminus is substantially different from the C-termini of all other examined mos proteins, suggesting that this region is nonessential and perhaps cleaved. Overall, v-mosm1 has greater homology with c-mos than does v-mos124, but mutually exclusive differences between c-mos and each of the v-mos genes preclude linear descent and suggest a common ancestral murine sarcoma virus.

J Virol. 1984 February; 49(2): 579-582






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Copyright © 1984 by the American Society for Microbiology. All rights reserved.