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J Virol. 1983 November; 48(2): 561-564

Monoclonal antibodies that inhibit attachment of group B coxsackieviruses.

B A Campbell and C E Cords

ABSTRACT

Hybridoma cell lines that secrete monoclonal antibodies which react with HeLa cell surface antigens were produced. The monoclonal antibodies prevented cytopathic effects caused by coxsackievirus B1 and significantly reduced the amounts of coxsackieviruses B1, B5, and B6 that absorb to HeLa cells. These antibodies did not protect the cells from poliovirus cytopathic effects, and they had no effect on the attachment of other picornaviruses to HeLa cells.

J Virol. 1983 November; 48(2): 561-564






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