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J Virol. 1982 August; 43(2): 749-752

Effects of fowlpox virus infection on lipid metabolism in cultured chicken embryo cells.

T M Buttke and L G Gafford

ABSTRACT

Lipid biosynthesis was measured in cultured chicken embryo cells after infection with fowlpox virus. Between 24 and 72 h postinfection, fowlpox virus-infected cells incorporated less [14C]acetate and 3H2O into fatty acids and sterols than did mock-infected cells, demonstrating a virus-dependent inhibition of general lipid metabolism. Two specific effects of fowlpox virus infection were an accumulation of C-4 alkylated sterol intermediates and inhibition of monounsaturated fatty acid biosynthesis.

J Virol. 1982 August; 43(2): 749-752






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Copyright © 1982 by the American Society for Microbiology. All rights reserved.