This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Street, J E Articles by Bellamy, A R Search for Related Content PubMed PubMed Citation Articles by Street, J E Articles by Bellamy, A R

Next Article 

J Virol. 1982 August; 43(2): 369-378

Sequence diversity of human rotavirus strains investigated by northern blot hybridization analysis.

ABSTRACT

Rotavirus genomic RNAs, derived from a series of human isolates that exhibit variability in the pattern of migration of the double-stranded RNA on polyacrylamide gels, were transferred to diazobenzyloxymethyl paper, and their sequence diversity was investigated. Hybridization of cDNA probes prepared from the 11 segments of rotavirus RNA indicated that considerable sequence diversity exists among these viruses. Under conditions of both low and high stringency, hybridization analysis of virus collected between 1975 and 1980 suggested that the variation among rotavirus strains may have occurred by a process involving both "drift" and "shift" in the sequence of the rotavirus genomic segments.

This article has been cited by other articles:

• Zhang, X., Settembre, E., Xu, C., Dormitzer, P. R., Bellamy, R., Harrison, S. C., Grigorieff, N. (2008). From the Cover: Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction. Proc. Natl. Acad. Sci. USA 105: 1867-1872 [Abstract] [Full Text]  
• Xu, A., Bellamy, A. R., Taylor, J. A. (1998). BiP (GRP78) and Endoplasmin (GRP94) Are Induced following Rotavirus Infection and Bind Transiently to an Endoplasmic Reticulum-Localized Virion Component. J. Virol. 72: 9865-9872 [Abstract] [Full Text]